Chantix

Q: Can I still buy Chantix?

Pfizer announced that it will stop producing <a href="https://www.withpower.com/clinical-trials/chantix">Chantix</a>, a <a href="https://www.withpower.com/clinical-trials/smoking-cessation">smoking cessation</a> pill, at the end of June 2021 due to the discovery of higher levels of nitrosamines, which are possible carcinogens, in the drug than what is considered acceptable.

Q: What does CHANTIX do to your body?

<a href="https://www.withpower.com/clinical-trials/chantix">Chantix</a> works by delivering a one-two punch to <a href="https://www.withpower.com/clinical-trials/smoking">smoking</a>: It blocks nicotine from reaching receptors in the brain, which breaks the pleasure cycle of habitual smoking, and prevents cravings by releasing small amounts of dopamine.Oct 8, 2020 Chantix works by preventing nicotine from reaching receptors in the brain, which breaks the pleasure cycle of habitual smoking, and by releasing small amounts of dopamine to prevent cravings.

Smoke, Dry Eye Syndrome, Smoking Cessation

Treatment

2 FDA approvals

20 Active Studies for Chantix

Treatment for

Smoke

What is Chantix

VareniclineThe Generic name of this drug

Treatment SummaryVarenicline is a prescription drug used to help people quit smoking. It is a type of medicine called a nicotinic receptor partial agonist. This means it has special effects on certain types of receptors in the body. Varenicline can increase the risk of seizures and may cause people who drink alcohol while taking the drug to become aggressive or lose consciousness. Pfizer Inc is conducting a study to find out more about the safety of this drug, and the results will be released in late 2015. Until this study is completed, the FDA will keep a warning printed on the drug packaging.

Chantixis the brand name

image of different drug pills on a surface

Chantix Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Chantix

Varenicline

2006

Approved as Treatment by the FDA

Varenicline, also called Chantix, is approved by the FDA for 2 uses which include Smoking Cessation and Smoke .

Smoking Cessation

Smoke

Effectiveness

How Chantix Affects PatientsVarenicline is a drug designed to activate the parts of the brain that nicotine usually stimulates, while blocking nicotine from attaching to those parts.

How Chantix works in the bodyVarenicline is a drug that helps people quit smoking by attaching itself to the same receptors that nicotine attaches to in the brain. It is much weaker than nicotine, so it doesn't make you feel as good, but it helps reduce the urge to smoke and can help with withdrawal symptoms. It is highly selective, meaning it only affects certain receptors and not others, so it's safer than many other drugs.

When to interrupt dosage

The suggested amount of Chantix is based upon the identified condition, such as Dry Eye Syndrome, Smoking Cessation and Smoke. Dosage is contingent upon the method of delivery (e.g. Tablet, film coated or Kit; Tablet) specified in the table underneath.

Condition

Dosage

Administration

Smoke

, 0.5 mg, 1.0 mg, 1.5 mg, 3.0 mg/mL

, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Tablet, Tablet - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit - Oral, Spray, Spray - Nasal, Nasal

Dry Eye Syndrome

, 0.5 mg, 1.0 mg, 1.5 mg, 3.0 mg/mL

, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Tablet, Tablet - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit - Oral, Spray, Spray - Nasal, Nasal

Smoking Cessation

, 0.5 mg, 1.0 mg, 1.5 mg, 3.0 mg/mL

, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Tablet, Tablet - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit - Oral, Spray, Spray - Nasal, Nasal

Warnings

There are 20 known major drug interactions with Chantix.

Common Chantix Drug Interactions

Drug Name

Risk Level

Description

Clofarabine

Major

The serum concentration of Clofarabine can be increased when it is combined with Varenicline.

Dalfampridine

Major

The serum concentration of Dalfampridine can be increased when it is combined with Varenicline.

Dofetilide

Major

The serum concentration of Dofetilide can be increased when it is combined with Varenicline.

Gentamicin

Major

The serum concentration of Gentamicin can be increased when it is combined with Varenicline.

Oxaliplatin

Major

The serum concentration of Oxaliplatin can be increased when it is combined with Varenicline.

image of a doctor in a lab doing drug, clinical research

Chantix Novel Uses: Which Conditions Have a Clinical Trial Featuring Chantix?

94 active trials are currently being conducted to assess the potential of Chantix to promote Smoking Cessation, Dry Eye Syndrome and Smoke Abstinence.

Condition

Clinical Trials

Trial Phases

Dry Eye Syndrome

14 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4

Smoke

0 Actively Recruiting

Smoking Cessation

99 Actively Recruiting

Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1, Phase 3

Chantix Reviews: What are patients saying about Chantix?

5Patient Review

5/6/2021

Chantix for Stop Smoking

I was a 44 year smoker who had tried to quit many times before. I decided to try Champix and by the end of the first packet, I had stopped smoking. I only experienced side effects like feeling nauseous when thinking about cigarettes after day 8. I didn't even need the second month's dose but kept them on hand just in case. It's been 16 months since I've smoked and I don't even crave cigarettes when around other smokers

5Patient Review

5/12/2021

Chantix for Stop Smoking

Chantix was a game-changer for me. I'd been trying to quit smoking on my own for years without success, but this medication really helped to lessen my urges. After just two weeks, I was able to stop completely!

5Patient Review

7/5/2021

Chantix for Stop Smoking

I started chantix while I was in rehab for my nicotine addiction. I wanted to avoid becoming dependent on other nicotine replacement therapies like patches, so I decided to try this medication. It's been over two months now and I haven't smoked at all. I still have strong cravings occasionally, but this drug has definitely helped me kick my habit for good.

5Patient Review

12/15/2021

Chantix for Stop Smoking

My wife and I started taking Chantix, and we were both able to quit smoking within a month. We still haven't gone back, 20 months later. If you're struggling to quit smoking, I highly recommend giving this drug a try.

5Patient Review

6/22/2021

Chantix for Stop Smoking

This treatment is amazing. I never really wanted to quit smoking, but I knew I needed to. This took away my cravings and allowed me to stand next to smokers without being bothered by the smell.

5Patient Review

4/29/2022

Chantix for Stop Smoking

I had smoked for over 52 years and tried to quit at least 15 times before I finally found success with chantix. I've now been smoke-free for 2 1/2 years with no withdrawal symptoms.

5Patient Review

10/26/2022

Chantix for Stop Smoking

Chantix has been a total gamechanger for me. I haven't had a cigarette in 16 years and it's all thanks to this medication.

5Patient Review

2/2/2021

Chantix for Stop Smoking

This medication was successful for me. I recommend getting a prescription for ativan from your doctor or psychiatrist to help with the depression and anxiety caused by chantix. I also suggest having Nicoderm patches on hand to deal with cravings.

4.3Patient Review

4/13/2021

Chantix for Stop Smoking

So far, this has been the most successful attempt I've made to quit smoking. I'm not experiencing nicotine cravings, and deep breathing has really helped with stress management. That said, I did have some nausea when taking the recommended two pills per day; cutting back to one pill has alleviated that issue.

3.7Patient Review

12/14/2020

Chantix for Stop Smoking

I have experienced some negative side effects, like nightmares and pressure in the back of my head. However, this medication is still helpful and I stopped taking it because I returned to smoking cigarettes.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about chantix

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Chantix do to your body?

"Chantix works by interfering with the brain's pleasure response to smoking and by releasing small amounts of dopamine to help reduce cravings."

Answered by AI

How long does it take to quit smoking with CHANTIX?

"A healthcare provider can prescribe CHANTIX to help adults stop smoking. The length of time that you take the medication depends on your quit approach."

Answered by AI

Can you still buy CHANTIX?

"On September 20, 2021, pharmaceutical manufacturer Pfizer announced that they would be halting the global production of Chantix (varenicline) due to the discovery of higher levels of nitrosamines - possible carcinogens - in the drug than what is considered acceptable."

Answered by AI

How long does it take to quit smoking with Chantix?

"With CHANTIX, you can choose one of several ways to set your quit date: you can choose to smoke your last cigarette 1 week after starting CHANTIX, up to 1 month after starting CHANTIX, or if you are sure that you cannot quit that abruptly, you can start CHANTIX and then cut your smoking in half each month, with the ...

With CHANTIX, you can choose one of several ways to set your quit date: you can choose to smoke your last cigarette 1 week after starting CHANTIX, up to 1 month after starting CHANTIX, or if you are sure that you cannot quit that abruptly, you can start CHANTIX and then cut your smoking in half each month, with the ...

Answered by AI

Can I still buy Chantix?

"Pfizer announced that it will stop producing Chantix, a smoking cessation pill, at the end of June 2021 due to the discovery of higher levels of nitrosamines, which are possible carcinogens, in the drug than what is considered acceptable."

Answered by AI

Does Chantix get you high?

"Approximately 1 in 1,000 patients who took CHANTIX in clinical trials reported feeling euphoric. A higher dose of CHANTIX (more than 2 mg) caused more frequent reports of gastrointestinal issues like nausea and vomiting."

Answered by AI

What does CHANTIX do to your body?

"Chantix works by delivering a one-two punch to smoking: It blocks nicotine from reaching receptors in the brain, which breaks the pleasure cycle of habitual smoking, and prevents cravings by releasing small amounts of dopamine.Oct 8, 2020

Chantix works by preventing nicotine from reaching receptors in the brain, which breaks the pleasure cycle of habitual smoking, and by releasing small amounts of dopamine to prevent cravings."

Answered by AI

Does CHANTIX get you high?

"Euphoria was reported by fewer than 1 out of 1,000 patients in clinical trials with CHANTIX. CHANTIX produced more frequent reports of gastrointestinal disturbances, such as nausea and vomiting, at higher doses (greater than 2 mg)."

Answered by AI