What side effects are associated with this type of intervention?

Common treatments for smoking cessation include pharmacotherapy (such as nicotine replacement therapy, varenicline, and bupropion) and behavioral interventions (such as counseling and digital tools like email communications and web-based tools). Known side effects of nicotine replacement therapy can include nausea, headaches, and insomnia. Varenicline may cause nausea, vivid dreams, and mood changes, while bupropion can lead to dry mouth, insomnia, and an increased risk of seizures. Behavioral interventions generally have minimal side effects, though some individuals may experience temporary increases in anxiety or irritability as they adjust to quitting smoking.

What prior FDA approvals exist?

The FDA has approved several pharmacologic treatments for smoking cessation, including bupropion and varenicline. These medications are considered first-line agents for assisting smoking cessation in adults. In addition to pharmacologic treatments, digital interventions such as web-based tools and mobile apps have been explored for their effectiveness in smoking cessation. These digital strategies, similar to the LungTalk web-based tool being studied, aim to increase awareness and knowledge about smoking cessation through various forms of communication, including text, audio, video, and animation.

What other types of research exist?

Promising, novel alternatives for smoking cessation include: 1) Text messaging programs, such as SmokefreeMOM and QuitNowTXT, which have shown effectiveness in different populations. 2) Hybrid phone counseling and text messaging interventions, which provide support through multiple communication channels. 3) Social network-based interventions like Tweet2Quit, which leverage peer support through platforms like Twitter. These alternatives offer diverse and accessible options for smoking patients considering treatment in 2024.

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LungTalk for Increasing Lung Cancer Screening

Q: What is the mechanism of action of this treatment?

Common treatments for smoking cessation include behavioral approaches, pharmacotherapy, and digital interventions. Behavioral approaches, such as counseling and motivational interviewing, help patients develop coping strategies and increase motivation to quit. Pharmacotherapy, including nicotine replacement therapy (NRT), varenicline, and bupropion, works by reducing withdrawal symptoms and cravings. Digital interventions, like the LungTalk web-based tool, use multimedia to educate and support patients. These treatments are crucial as they address both the physical addiction and psychological aspects of smoking, increasing the likelihood of successful cessation.

Phase < 1

Waitlist Available

Led By Lisa Carter-Harris, PhD, NP, RN

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Women who currently smoke or quit within past 15 years as per self report

Age 50-80 years

Must not have

Lung cancer diagnosis

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to use emails and an online tool called LungTalk to educate women who have had a mammogram about lung cancer screening. The goal is to increase their awareness and knowledge using easy-to-understand digital content.

Who is the study for?

This trial is for women aged 50-80 who have a history of heavy smoking (at least 20-pack-years), either currently smoke or quit within the last 15 years, and haven't had lung cancer screening before. They must have recently had a mammogram with no signs of breast cancer.

What is being tested?

The study is testing 'LungTalk', a digital tool designed to raise awareness about lung cancer screening through emails and an interactive web-based platform featuring text, audio, video, and animations.

What are the potential side effects?

Since this trial involves educational material rather than medical treatment, there are no direct physical side effects. However, participants may experience increased anxiety or concern regarding their health due to information received.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am a woman who has smoked in the last 15 years.

Select...

I am between 50 and 80 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have been diagnosed with lung cancer.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Number of participants accrued through digital outreach to identify breast screening participants eligible for lung screening

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Women who have had a mammogramExperimental Treatment1 Intervention

Participants will consist of eligible women who have had a mammogram

0 / 3Eligibility criteria met

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Common treatments for smoking cessation include behavioral approaches, pharmacotherapy, and digital interventions. Behavioral approaches, such as counseling and motivational interviewing, help patients develop coping strategies and increase motivation to quit. Pharmacotherapy, including nicotine replacement therapy (NRT), varenicline, and bupropion, works by reducing withdrawal symptoms and cravings. Digital interventions, like the LungTalk web-based tool, use multimedia to educate and support patients. These treatments are crucial as they address both the physical addiction and psychological aspects of smoking, increasing the likelihood of successful cessation.

Effectiveness of pharmacotherapy for smoking cessation: protocol for umbrella review and quality assessment of systematic reviews.Accuracy of popular media reporting on tobacco cessation therapy in substance abuse and mental health populations.