← Back to Search

Small Molecule

A Study of JNJ-67484703 in Participants With Active Rheumatoid Arthritis

Phase 1
Waitlist Available
Research Sponsored by Janssen Research & Development, LLC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 24 weeks

Summary

This trial is testing JNJ-67484703, a specially designed antibody, in people with active rheumatoid arthritis. The treatment aims to help the immune system stop attacking its own tissues, which can reduce inflammation and symptoms.

Eligible Conditions
  • Rheumatoid Arthritis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 24 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Percentage of Participants with Abnormalities in Laboratory Parameters
Percentage of Participants with Abnormalities in Physical Examination
Percentage of Participants with Abnormalities in Vital Signs
+3 more
Secondary study objectives
Change from Baseline in Disease Activity Index Score 28 using C-reactive Protein (DAS28-CRP) at Week 12
Change in Magnitude and Duration of Cell Surface Expression Level of Receptors
Change in Number of T-lymphocyte Populations in Blood
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: JNJ-67484703Experimental Treatment1 Intervention
Participants will receive multiple doses of JNJ-67484703.
Group II: PlaceboPlacebo Group1 Intervention
Participants will receive multiple doses of placebo.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
JNJ-67484703
2021
Completed Phase 1
~50

Find a Location

Who is running the clinical trial?

Janssen Research & Development, LLCLead Sponsor
1,007 Previous Clinical Trials
6,402,326 Total Patients Enrolled
5 Trials studying Rheumatoid Arthritis
678 Patients Enrolled for Rheumatoid Arthritis
Janssen Research & Development, LLC Clinical TrialStudy DirectorJanssen Research & Development, LLC
772 Previous Clinical Trials
3,980,353 Total Patients Enrolled
2 Trials studying Rheumatoid Arthritis
278 Patients Enrolled for Rheumatoid Arthritis
~11 spots leftby Dec 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top