Stem Cells for Retinal Disease

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 1

Waitlist Available

Sponsor: University of California, Davis

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial is testing if injecting special cells from bone marrow into the eye is safe and possible for patients who are permanently blind due to retinal diseases. The hope is that these cells can help fix the damaged parts of their eyes.

Research Team

Susanna s Park, MD PhD

Principal Investigator

University of California Davis Eye Center

Eligibility Criteria

This trial is for adults over 18 with vision loss from conditions like macular degeneration or diabetic retinopathy. Participants must have a visual acuity ranging from 20/100 to hand movement and the affected eye should be the one with worse vision. They shouldn't have had certain eye treatments in the last 6 months, no blood disorders, active diseases, or be on immunosuppressive therapy.

Inclusion Criteria

Visual acuity 20/100 to CF

I am older than 18 years.

I have vision loss due to a specific eye condition.

Exclusion Criteria

Allergy to fluorescein dye

I have an eye condition affecting my vision.

Treatment Details

Interventions

• CD34+ bone marrow stem cells (Stem Cell Therapy)

Trial Overview The study tests injecting CD34+ stem cells directly into the eye of patients who are blind due to various retinal diseases. It aims to assess if this approach is safe and can feasibly improve sight.

Participant Groups

Group I: Stem cell treated Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

University of California, Davis

Lead Sponsor

Trials

958

Recruited

4,816,000+