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CBD Oil for Scar Healing

Phase 1
Waitlist Available
Research Sponsored by University of Oklahoma
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Must not have
Patients younger than 18 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years

Summary

This trial is testing if CBD oil can improve the appearance of forehead scars. It may have anti-inflammatory benefits that can help keep skin healthy.

Who is the study for?
Adults of any gender or ethnicity who have had a Paramedian forehead flap (PMFF) surgery are eligible for this study. It's not suitable for anyone under 18 or those with allergies to CBD.
What is being tested?
The trial is testing if applying CBD oil, known for its anti-inflammatory effects, on forehead scars can improve their appearance. Participants will use a silicone patch combined with flavorless CBD tincture compared to just the silicone patch.
What are the potential side effects?
CBD oil may cause skin irritation at the site of application, mild itching, redness, or rash. Systemic side effects are unlikely as it's used topically but could include fatigue or changes in appetite.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am under 18 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Proportion of CBD Oil's Impact on postoperative scars in paramedian forehead flap reconstruction patients.

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Split-scar randomized trial arm with CBD oilExperimental Treatment1 Intervention
The study targets the vertical forehead scar, treating half with CBD oil and a silicone patch (experimental).
Group II: Split-scar randomized trial arm without CBD oilPlacebo Group1 Intervention
The study targets the vertical forehead scar, treating half with a silicone patch (control).

Find a Location

Who is running the clinical trial?

University of OklahomaLead Sponsor
474 Previous Clinical Trials
93,672 Total Patients Enrolled
~15 spots leftby Jun 2026