~13 spots leftby Dec 2026

Augmented Visual Feedback for Stroke Rehabilitation

Recruiting in Palo Alto (17 mi)
Overseen byJames Patton
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Shirley Ryan AbilityLab
No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this research study is to increase understanding of error augmentation by applying it to visual feedback during motion tracking with a Leap Motion device - a recently developed optical hand tracking tool - and the LookingGlass - a new, portable virtual reality environment. In conjunction with the Leap, large, three dimensional work spaces can provide an immersive and virtual augmented environment for rehabilitation. Previously, experiments have utilized the Virtual Reality Robotic and Optical Operations Machine (VRROOM) to create such visually immersive environments. The Robotics lab as part of the Arms and Hands Lab on the 22nd floor of the Shirley Ryan Abilitylab has developed a portable version of this system, which is more compact and clinic-compatible. Combining this visual 3D system with the Leap creates a novel, more capable apparatus for studying error augmentation. This research study will have 3 different arms: 1.) a healthy group of individuals (Healthy Arm), 2.) a group of stroke survivors within 8 months of stroke (Acute Arm), and 3.) a group of stroke survivors that had their stroke more than 8 months ago (Chronic Arm). Each Arm will use the Leap motion tracker and the Looking Glass to participate in a reaching intervention. The healthy arm will only participate in 1 visit with an intervention with and without error augmented visual feedback. The Acute Arm and the Chronic Arm will both have 2 groups: 1.) Error Augmented Visual Feedback group and 2.) Non-Augmented or Veridical Visual Feedback group. The Chronic Arm will have a structured intervention and evaluation protocol: Study staff will administer outcome assessments at 3 time points: a.) prior to intervention, b.) post intervention, and c.) 2 months after the conclusion of intervention. Intervention will occur over the span of 6-8 weeks with the goal of 3 1-hour sessions per week. The Acute Arm will have a less structured intervention that will occur while the participant is an inpatient at Shirley Ryan AbilityLab. Study staff will administer outcome assessments at at least 2 time points: a.) prior to intervention, b.) post intervention just prior to discharge from Shirley Ryan AbilityLab. Between initial and post intervention evaluations, midpoint evaluations will take place at a maximum of once per week if the participant's schedule, activity tolerance, and length of stay allows. Intervention will consist of 1-hour sessions occurring according to the availability of the participant at the rate of no more than 2 sessions in a 24 hour period. Investigators hope to investigate these questions: 1. Can the movement of healthy individuals be characterized with error augmented visual feedback and veridical visual feedback? 2. Will error augmented visual feedback or veridical visual feedback result in greater movement ability improvement? Investigators hypothesize that in the Chronic Arm, those what trained with error-augmented visual feedback will have improved movement ability compared to those who trained with veridical visual feedback. 3. Is treatment with the looking glass and leap system feasible with an inpatient population? Investigators hypothesize that this treatment will be feasible for an inpatient population.

Eligibility Criteria

This trial is for adults who had a stroke at least 8 months ago, can move their shoulder and elbow against gravity to reach forward, but not for those with severe muscle stiffness, recent Botox in the arm, or other rehab treatments. It excludes pregnant women, children, prisoners, people with multiple strokes or severe sensory issues in the limb.

Inclusion Criteria

You had a stroke 8 months ago.
I'm not familiar with the term "FMUE 15-50." Can you provide more context or information so I can assist you better?
You are able to move your shoulder and elbow to reach 30 cm in different directions.

Exclusion Criteria

You are not able to stay in the required testing positions.
You have major loss of feeling in the affected limb.
You have very severe muscle stiffness that makes it hard to move your elbow.
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Treatment Details

Interventions

  • Augmented Visual Feedback (Behavioural Intervention)
  • Bimanual Balanced Reaching With Visual Biofeedback (Behavioural Intervention)
  • Healthy Comparative Reaching Task (Behavioural Intervention)
  • Leap Motion Device (Behavioural Intervention)
  • Looking Glass (Behavioural Intervention)
  • Veridical Visual Feedback (Behavioural Intervention)
Trial OverviewThe study tests if augmented visual feedback using Leap Motion and Looking Glass helps improve movement more than standard feedback. Participants are divided into healthy individuals; acute stroke survivors (recent stroke); and chronic survivors (older stroke), each receiving different interventions.
Participant Groups
5Treatment groups
Experimental Treatment
Active Control
Group I: Chronic Veridical Visual FeedbackExperimental Treatment1 Intervention
Reaching while sitting at the Looking Glass system. The representation of arm movements will directly reflect the participants actual arm movements.
Group II: Chronic Augmented Visual FeedbackExperimental Treatment1 Intervention
Reaching while sitting at the Looking Glass system. The representation of a participant's arm movements will be augmented to encourage different movement patterns and improved movement.
Group III: Acute Veridical Visual FeedbackExperimental Treatment1 Intervention
Reaching while sitting at the Looking Glass system. The representation of arm movements will directly reflect the participants actual arm movements.
Group IV: Acute Augmented Visual FeedbackExperimental Treatment1 Intervention
Reaching while sitting at the Looking Glass system. The representation of a participant's arm movements will be augmented to encourage different movement patterns and improved movement.
Group V: HealthyActive Control1 Intervention
Healthy participants will participate in reaching activity using the Looking Glass and Leap motion tracking system

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Shirley Ryan AbilityLabChicago, IL
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Who Is Running the Clinical Trial?

Shirley Ryan AbilityLabLead Sponsor

References