← Back to Search

Serotonin and Norepinephrine Reuptake Inhibitor

Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes

Phase 2 & 3

Waitlist Available

Led By Habib Rizk, MD

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Summary

This trial tests venlafaxine, a medication for depression and anxiety, on patients with Meniere's disease. The goal is to see if it can help reduce vertigo and other symptoms by balancing brain chemicals. Venlafaxine is the first member of a new class of antidepressants that affects both serotonin and norepinephrine.

Eligible Conditions

Meniere's Disease

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Number of Vertigo Episodes

Severity of Vertigo

Secondary study objectives

Change in Score on Cognitive Failure Questionnaire (CFQ)

Change in Score on Dizziness Handicap Inventory (DHI)

Change in Score on Neuropsychological Vertigo Inventory (NVI)

+4 more

Side effects data

From 2009 Phase 4 trial • 220 Patients • NCT00177671

Suicide Attempt

Myocardial infarcation with congestive heart failure

stroke

100%

80%

60%

40%

20%

Study treatment Arm

Donepezil

Placebo

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Venlafaxine ArmExperimental Treatment1 Intervention

Group II: PlaceboPlacebo Group1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Venlafaxine

2007

Completed Phase 4

~3259640

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Cures Within ReachOTHER

23 Previous Clinical Trials

2,119 Total Patients Enrolled

American Hearing Research FoundationUNKNOWN

Cures within Reach FoundationUNKNOWN

Medical University of South CarolinaLead Sponsor

977 Previous Clinical Trials

7,400,947 Total Patients Enrolled

Habib Rizk, MD3.58 ReviewsPrincipal Investigator - Medical University of South Carolina

Medical University of South Carolina

5Patient Review

I had a great experience with Dr. Rizk. He was very understanding and considerate of my inner ear issues from chemo/radiation damage. He wrote me a very reassuring letter with the test results.