~7 spots leftby Dec 2025

High-density Microelectrode for Parkinson's Disease

Recruiting in Palo Alto (17 mi)
Adam Mamelak Profile | Cedars-Sinai ...
Overseen byAdam Mamelak, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Cedars-Sinai Medical Center
No Placebo Group

Trial Summary

What is the purpose of this trial?The purpose of this study is to test the ability of a newly-designed electrode to measure the activity of individual nerve cells (neurons), and collections of nerve cells (local field potentials) in the brain. The study's main goals are to see how well this electrode works compared to standard electrodes and to validate its safety.

Eligibility Criteria

This trial is for adults over 18 with Parkinson's Disease who are undergoing a Deep Brain Stimulating (DBS) electrode implant in the brain to improve treatment. They must be able to consent and have no allergies to stainless steel or polyimide, nor previous DBS implants at the site.

Inclusion Criteria

I am older than 18 years.
I can understand and agree to the study's details on my own.
I am getting a DBS implant for Parkinson's to better locate the STN.

Exclusion Criteria

Microelectrode recording is not indicated
Previous implantation of DBS electrodes in this site
Known allergic reaction to stainless steel or polyimide

Participant Groups

The study tests a new high-density microelectrode designed for recording individual and group nerve cell activity in the human brain. It aims to compare its performance and safety against standard electrodes during DBS procedures.
1Treatment groups
Experimental Treatment
Group I: Neuronal Recording and Behavioral TestingExperimental Treatment1 Intervention
Neuronal Recording and Behavioral Testing

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Cedars-Sinai Medical CenterLos Angeles, CA
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Who Is Running the Clinical Trial?

Cedars-Sinai Medical CenterLead Sponsor

References