SPG Block for Anxiety

Recruiting at 3 trial locations

Overseen By Anthony V Seto, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 2

Waitlist Available

Sponsor: University of Calgary

Prior Safety Data

Trial Summary

What is the purpose of this trial?

The goal of this clinical trial is to learn about the effect of a sphenopalatine ganglion (SPG) block in anxious patients at electronic dance music festivals. The main question is: - Is an SPG block useful in reducing anxiety, in comparison to placebo? Participants will have lidocaine-soaked cotton tip applicator placed inside each nare for 10-minutes, or have a saline-soaked cotton tip applicator placed inside each nare for 10-minutes. Researchers compare the lidocaine-soaked intervention (SPG block) with the saline-soaked intervention (placebo) to see if it reduces anxiety in patients presenting at electronic dance music festivals with anxiety.

Research Team

Anthony V Seto, MD

Principal Investigator

University of Calgary

Eligibility Criteria

This trial is for adults over 18 who are attending an electronic dance music festival and feel anxious, rating their anxiety at least a 1 out of 10. They shouldn't have taken any anti-anxiety meds since arriving at the festival or have issues that prevent cotton applicators from being placed in their nose, like a nosebleed or allergy to lidocaine.

Inclusion Criteria

I experience some level of anxiety.

I am 18 years old or older.

Exclusion Criteria

I haven't taken any anti-anxiety medication given by festival medical staff.

Known allergy to lidocaine

I cannot have anything inserted into my nose due to blockage or other issues.

Treatment Details

Interventions

• Lidocaine 2% Injectable Solution (Local Anesthetic)
• Placebo (Procedure)

Trial Overview Researchers are testing if an SPG block with lidocaine can reduce anxiety compared to a placebo. Participants will get either lidocaine-soaked or saline-soaked cotton applicators in their nostrils for ten minutes to see which one better eases anxiety during the event.

Participant Groups

Group I: 2% Lidocaine Experimental Treatment 1 Intervention

1 cotton tip applicator, pre-soaked in 2% lidocaine, inserted into each nare, and left for 10 minutes

Group II: Placebo Placebo Group 1 Intervention

1 cotton tip applicator, pre-soaked in saline, inserted into each nare, and left for 10 minutes

Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials

827

Recruited

902,000+