IV Iron Infusion for Cancer-Related Anemia

Phase 3

Waitlist Available

Led By Maryam Al-Hayki

Research Sponsored by University of Saskatchewan

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients on any active cancer treatment or with history of previous chemotherapy, surgery, radiation, PARP, biologics, and hormonal treatment

Perioperative patients having upfront surgery or at interval or secondary debulking surgery

Must not have

Palliative patients with life expectancy 6 months or less

Medical conditions with contraindication to IV iron infusion or blood transfusion (Example: iron overload, hemosiderosis, decompensated liver cirrhosis, or active hepatitis)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up hgb will be checked just prior to treatment and then biweekly until week 8 or whenever hgb rises at least by 20 g/l through the treatment period, upto 3 years.

Awards & highlights

Pivotal Trial

No Placebo-Only Group

Summary

This trial aims to investigate the use of intravenous (IV) iron infusion in managing anemia in patients with ovarian cancer. Anemia is a common issue in cancer patients and can impact their treatment outcomes

Who is the study for?

This trial is for ovarian cancer patients who are experiencing anemia, either as a new symptom or during their cancer treatment. It's important that participants have not had any iron treatments recently and do not have other medical conditions that could affect the study results.

What is being tested?

The trial is testing whether giving iron directly into the bloodstream can help with anemia in people with ovarian cancer. The goal is to see if this improves how long they live, their energy levels, and overall well-being.

What are the potential side effects?

Possible side effects of IV iron infusion include allergic reactions, infections at the injection site, changes in blood pressure, headaches, dizziness, nausea or vomiting.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had cancer treatments like chemotherapy, surgery, or hormone therapy.

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I am scheduled for or have had surgery to remove a tumor.

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I am a woman aged 18 or older.

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I am fit for cancer treatment and expected to live more than 6 months.

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I have had 2 or fewer chemotherapy treatments.

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My ovarian cancer is confirmed and is stage IC-IV.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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My doctor expects I have 6 months or less to live.

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I don't have conditions that prevent IV iron or blood transfusions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ hgb will be checked just prior to treatment and then biweekly until week 8 or whenever hgb rises at least by 20 g/l through the treatment period, upto 3 years.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~hgb will be checked just prior to treatment and then biweekly until week 8 or whenever hgb rises at least by 20 g/l through the treatment period, upto 3 years.

This trial's timeline: 3 weeks for screening, Varies for treatment, and hgb will be checked just prior to treatment and then biweekly until week 8 or whenever hgb rises at least by 20 g/l through the treatment period, upto 3 years. for reporting.