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Procedure

Laser Ablation for Thyroid Cancer

Phase 2

Waitlist Available

Led By R. Michael Tuttle, MD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Preserved contralateral vocal cord function prior to PLA

Age ≥ 18 years

Must not have

Clinical or ultrasonographic evidence of lymph node metastasis

Thyroid cancer that is non papillary thyroid cancer (PTC)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether laser ablation is a safe and effective alternative to surgery for removing very small thyroid tumors.

Who is the study for?

This trial is for adults with a small thyroid cancer (≤13mm) called papillary thyroid microcarcinoma, who haven't spread to lymph nodes or beyond the thyroid capsule. It's for those who've declined just watching the tumor and have certain cancer cell characteristics confirmed by tests.

What is being tested?

The study is testing percutaneous laser ablation (PLA), which uses lasers to destroy tumors without surgery, as a treatment option for removing tiny papillary thyroid cancers instead of traditional surgery.

What are the potential side effects?

While not explicitly listed in your information, PLA may cause pain at the injection site, swelling, bruising, infection risk at the needle entry point and potential damage to surrounding tissues.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My other vocal cord works fine before the procedure.

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I am 18 years old or older.

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I have chosen not to undergo active surveillance for my condition.

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My thyroid cancer diagnosis is confirmed by specific tests and features.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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My cancer has spread to my lymph nodes.

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My thyroid cancer is not the papillary type.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Number of participants with complete thermal ablation

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Participants with papillary microcarcinoma (PTMC)Experimental Treatment1 Intervention

Participants with papillary microcarcinoma (PTMC) who have elected to proceed with thyroidectomy rather than an observational management approach will be considered as potential candidates for this trial.

0 / 6Eligibility criteria met