Trial Summary
What is the purpose of this trial?
The purpose of this study is to explore whether percutaneous laser ablation (PLA) is a safe and effective alternative to removing papillary thyroid microcarcinoma (PTMC) with surgery.
Research Team
RM
R. Michael Tuttle, MD
Principal Investigator
Memorial Sloan Kettering Cancer Center
Eligibility Criteria
This trial is for adults with a small thyroid cancer (≤13mm) called papillary thyroid microcarcinoma, who haven't spread to lymph nodes or beyond the thyroid capsule. It's for those who've declined just watching the tumor and have certain cancer cell characteristics confirmed by tests.Inclusion Criteria
My other vocal cord works fine before the procedure.
The size of the maximum diameter of something should be 13 millimeters or less.
Your medical scans do not show any signs of cancer spreading to the lymph nodes.
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Exclusion Criteria
My cancer has spread to my lymph nodes.
Pregnancy
Your thyroid lesion has more than 25% cysts in it.
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Treatment Details
Interventions
- Percutaneous Laser Ablation (PLA) (Procedure)
Trial OverviewThe study is testing percutaneous laser ablation (PLA), which uses lasers to destroy tumors without surgery, as a treatment option for removing tiny papillary thyroid cancers instead of traditional surgery.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Participants with papillary microcarcinoma (PTMC)Experimental Treatment1 Intervention
Participants with papillary microcarcinoma (PTMC) who have elected to proceed with thyroidectomy rather than an observational management approach will be considered as potential candidates for this trial.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Memorial Sloan Kettering Cancer Center
Lead Sponsor
Trials
1,998
Recruited
602,000+
Lisa M. DeAngelis
Memorial Sloan Kettering Cancer Center
Chief Medical Officer since 2021
MD from Columbia University
Selwyn M. Vickers
Memorial Sloan Kettering Cancer Center
Chief Executive Officer since 2022
MD from Johns Hopkins University