Low-Dose Radiation Therapy for Mycosis Fungoides

Recruiting in Palo Alto (17 mi)

Overseen ByBouthaina S Dabaja

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: Phase 2

Recruiting

Sponsor: M.D. Anderson Cancer Center

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?This phase II trial studies how well ultra low dose radiation therapy works in treating patients with mycosis fungoides. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving ultra low doses of radiation may help control the disease and reduce side effects compared to treatment with higher doses.

Eligibility Criteria

This trial is for patients with mycosis fungoides, a type of skin lesion. Eligible participants can have any stage of the disease and may be undergoing other treatments. They must not apply certain topical agents to the lesion before joining, and women who can become pregnant need a negative pregnancy test.

Inclusion Criteria

I have mycosis fungoides with skin symptoms.

I have at least one visible tumor that can be measured.

Exclusion Criteria

I have active lupus or scleroderma.

My skin lesions are not taller than 1 cm from the surface.

Participant Groups

The study tests ultra low dose radiation therapy's effectiveness in treating mycosis fungoides. It aims to control the disease with fewer side effects than higher doses. Patients' quality of life will also be assessed through questionnaires.

1Treatment groups

Experimental Treatment

Group I: Treatment (ultra low dose radiation therapy)Experimental Treatment3 Interventions

Patients undergo ultra low dose radiation therapy at the discretion of the treating physician.