~14 spots leftby Apr 2026

A Multicenter, Open-Label Trial to Evaluate the Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg in Patients With Post-Operative Pain

Recruiting at 1 trial location
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 3
Waitlist Available
Sponsor: Talphera, Inc
No Placebo Group
Pivotal Trial (Near Approval)
Prior Safety Data

Trial Summary

What is the purpose of this trial?

This is a multicenter, open-label study in patients 40 years and older who are undergoing a surgical procedure. Patients may receive one dose of ST 30 mcg as needed for pain management, but no more frequently than every 60 minutes, for up to 12 hours.

Research Team

PP

Pamela P. Palmer, MD, PhD

Principal Investigator

Talphera, Inc

Eligibility Criteria

Inclusion Criteria

Male or female patients who are 40 years of age or older.
Patients who have undergone a surgical procedure with general anesthesia or spinal anesthesia that does not include intrathecal opioids during the operation.
Patients classified as American Society of Anesthesiologists (ASA) class IIII (Appendix I).

Treatment Details

Interventions

  • Sufentanil Sublingual Tablet 30 mcg (Opioid Analgesic)
Participant Groups
1Treatment groups
Experimental Treatment
Group I: sufentanil sublingual tablet 30 mcgExperimental Treatment1 Intervention
sufentanil sublingual tablet 30 mcg

Find a Clinic Near You

Who Is Running the Clinical Trial?

Talphera, Inc

Lead Sponsor

Trials
18
Recruited
2,300+

AcelRx Pharmaceuticals, Inc.

Lead Sponsor

Trials
17
Recruited
2,200+