Adapt2Quit Motivational System for Quitting Smoking
(A2Q Trial)
Recruiting in Palo Alto (17 mi)
+2 other locations
Overseen ByRajani Sadasivam, PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: University of Massachusetts, Worcester
No Placebo Group
Approved in 1 jurisdiction
Trial Summary
What is the purpose of this trial?This trial tests a computer program called Adapt2Quit that sends personalized motivational texts to help socioeconomically disadvantaged smokers quit. The program uses user feedback to choose the most motivating messages.
Do I have to stop taking my current medications to join the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the idea that Adapt2Quit Motivational System for Quitting Smoking is an effective treatment?
The available research does not provide specific data on the effectiveness of the Adapt2Quit Motivational System for Quitting Smoking. However, it does mention the effectiveness of another treatment, the Pathways to Change system, which is an expert system intervention for smoking cessation. This system showed cessation rates of 22 to 26% in a general population, with increasing effects over time. This suggests that expert system interventions, like Adapt2Quit, could potentially be effective in helping people quit smoking.
12345What safety data is available for the Adapt2Quit smoking cessation treatment?
The provided research does not directly mention safety data for the Adapt2Quit treatment or its variants. The studies focus on other smoking cessation methods, such as smartphone applications, electronic cigarettes, text messaging programs, and chat-bots, but do not provide specific safety data for Adapt2Quit.
678910Is the Adapt2Quit treatment a promising way to quit smoking?
The Adapt2Quit treatment seems promising because similar systems, like SmartQuit and Text2Quit, have shown success in helping people quit smoking. These systems use technology to provide support and advice, which can make quitting easier and more effective.
58111213Eligibility Criteria
This trial is for English-speaking adults who smoke, have had at least two clinical visits in the past year, and are socioeconomically disadvantaged. They must own a texting-enabled cell phone. Pregnant women, prisoners, those unable to consent, minors, and previous pilot study participants cannot join.Inclusion Criteria
Active in care (at least two clinical visits in the last year)
You are currently smoking.
I speak English.
+2 more
Exclusion Criteria
Pilot study participants
I am unable to give consent for medical procedures.
Pregnant women
+3 more
Participant Groups
The Adapt2Quit program is being tested against a control that only facilitates quitline use via text messages. The program sends motivational texts tailored to help users quit smoking based on their feedback on message effectiveness.
2Treatment groups
Experimental Treatment
Active Control
Group I: Adapt2QuitExperimental Treatment1 Intervention
These participants will receive Adapt2Quit motivational messaging and quitline facilitation messaging for 6 months.
Group II: ControlActive Control1 Intervention
These participants will receive quitline facilitation-only messaging for 6 months.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Johns Hopkins UniversityBaltimore, MD
Baystate HealthSpringfield, MA
University of Massachusetts Medical SchoolWorcester, MA
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Who Is Running the Clinical Trial?
University of Massachusetts, WorcesterLead Sponsor
Johns Hopkins UniversityCollaborator
National Cancer Institute (NCI)Collaborator
Baystate HealthCollaborator
National Institutes of Health (NIH)Collaborator
References
Measuring fidelity to behavioural support delivery for smoking cessation and its association with outcomes. [2021]Behavioural support increases smoking cessation in clinical settings, but effect sizes differ among providers, due possibly to variations in delivery. This study evaluates a measure ('fidelity index') intended to capture fidelity to delivery of content- and interaction-based items of a behavioural support (BS) for smoking cessation and the association of fidelity with quit rates.
Evaluating four motivation-phase intervention components for use with primary care patients unwilling to quit smoking: a randomized factorial experiment. [2022]To assess the effectiveness of intervention components designed to increase quit attempts and promote abstinence in patients initially unwilling to quit smoking.
Can we increase smokers' adherence to nicotine replacement therapy and does this help them quit? [2019]To examine the effects of five intervention components on smokers' adherence to combined nicotine patch and nicotine gum during a quit attempt and assess whether adherence is related to cessation.
Assessing motivation to smoking cessation in hospitalized patients. [2021]To assess motivation to quit smoking in patients admitted to an acute care hospital, determine predictors of readiness to change, and identify a risk group that requires targeted motivational interviewing.
An expert system intervention for smoking cessation. [2022]The Pathways to Change system (PTC) is an expert system intervention for smoking cessation. Assessments are performed either by mail or by a telephone interview and each smoker receives a three- to four-page report that provides individualized recommendations matched to the individual's needs and readiness-to-change. The Transtheoretical Model of Change provides the theoretical basis for the expert system. Four different studies have demonstrated the efficacy of this intervention in a general population, with cessation rates of 22 to 26%. Furthermore, the difference between the groups was larger at each follow-up assessment point, indicating that the effects of the treatment increased long after the end of treatment. The studies involved two proactively recruited samples, demonstrating that a large proportion (85.3% and 82.5%) of the population of smokers could be successfully recruited into a smoking cessation program. Expert system interventions have the potential to have an extremely high impact on a total population of smokers.
Effectiveness of a chat-bot for the adult population to quit smoking: protocol of a pragmatic clinical trial in primary care (Dejal@). [2020]The wide scale and severity of consequences of tobacco use, benefits derived from cessation, low rates of intervention by healthcare professionals, and new opportunities stemming from novel communications technologies are the main factors motivating this project. Thus, the purpose of this study is to assess the effectiveness of an intervention that helps people cease smoking and increase their nicotine abstinence rates in the long term via a chat-bot, compared to usual practice, utilizing a chemical validation at 6 months.
How do text-messaging smoking cessation interventions confer benefit? A multiple mediation analysis of Text2Quit. [2018]To determine the degree to which the observed benefit of Text2Quit was accounted for by psychosocial mechanisms derived from its quit smoking messaging versus from the use of extra-programmatic smoking cessation treatments and services.
Single-arm trial of the second version of an acceptance & commitment therapy smartphone application for smoking cessation. [2023]The first randomized trial of a smartphone application (app) for adult smoking cessation (SmartQuit 1.0) revealed key features that predict cessation. These findings guided the revision of this Acceptance & Commitment Therapy (ACT)-based application (SmartQuit 2.0), which was primarily tested to examine participant receptivity, short-term cessation and reduction, and the relationship between program completion, smoking cessation and reduction. Secondarily, outcomes were descriptively compared with the SmartQuit1.0 trial.
Piloting a clinical laboratory method to evaluate the influence of potential modified risk tobacco products on smokers' quit-related motivation, choice, and behavior. [2021]Research methods are needed that can predict whether the availability of potential modified risk tobacco products (MRTPs) may influence smokers' quit-related motivation, choice, and behavior. This pilot study assessed the primary outcomes of feasibility and adherence to address this need using an electronic cigarette (ECIG) as a model MRTP. Cigarette smokers were randomly assigned to use only their own brand of cigarettes (OB-only) or a second-generation ECIG (18 ng/ml nicotine) plus their OB cigarettes (ECIG+OB) ad libitum for four weeks. Participants logged products using a mobile device, collected used cigarette filters, and provided saliva samples every day for analysis of cotinine. They returned to the lab once per week to provide a breath sample and accept or decline a choice to quit all tobacco products (i.e., cigarettes and/or ECIGs). They also returned for a one-month follow-up visit. Of those participants randomized (n = 60), 56.7% completed the 4-week intervention and 40.0% completed the follow-up visit. The primary reason for withdrawal was poor adherence with mobile device use. Comparable numbers of participants in each group chose to make a quit attempt, although more OB-only participants chose to quit during the first two weeks and more ECIG+OB participants during the last two weeks. With protocol modifications to reduce participation burden, the current method might ultimately be used by regulators to predict how smokers' quit-related motivation, choice, and behavior are influenced by current and future MRTPs.
Analysing user-reported data for enhancement of SmokefreeTXT: a national text message smoking cessation intervention. [2018]This observational study highlights key insights related to participant engagement and cessation among adults who voluntarily subscribed to the nationwide US-based SmokefreeTXT program, a 42-day mobile phone text message smoking cessation program.
Patterns of use of an automated interactive personalized coaching program for smoking cessation. [2022]The QuitCoach, an "expert system" program of tailored advice for smoking cessation developed in Australia, has been publicly available since July 2003, albeit with limited promotion. The program is designed to be used on multiple occasions, guiding the user through the process of smoking cessation in the manner of a "life coach". Email reminders are sent at scheduled intervals to prompt optimal and repeated use.
Using SmartQuit®, an Acceptance and Commitment Therapy Smartphone application, to reduce smoking intake. [2022]SmartQuit® is a smartphone application (app) for smoking cessation based on Acceptance and Commitment Therapy, a behavioural therapy that encourages individuals to accept internal experiences, such as cravings to smoke, without acting on those experiences or urges. We used a single-subject (A-B-A) design with 10 participants to examine whether SmartQuit® use would reduce cigarette intake in a New Zealand sample.
A randomized trial of Text2Quit: a text messaging program for smoking cessation. [2022]Text messaging programs on mobile phones have shown some promise in helping people quit smoking. Text2Quit is an automated, personalized, interactive mobile health program that sends text messages to offer advice, support, and reminders about quitting smoking.