Trial Summary
What is the purpose of this trial?The aim of this phase is to examine the feasibility and acceptability of the Augmented Reality (AR)-based and electroencephalography (EEG)-based neglect detection and rehabilitation tool.
What safety data exists for augmented reality rehabilitation for stroke-related neglect?The provided research abstracts do not explicitly mention safety data for augmented reality rehabilitation systems like the AREEN System or NAMI App. They focus on efficacy and detection capabilities. For safety data, further investigation into full studies or clinical trial reports would be necessary.12345
What data supports the idea that Augmented Reality Rehabilitation for Stroke-Related Neglect is an effective treatment?The available research shows that the augmented reality app 'Negami' was tested in a study with 20 stroke patients and found to help improve attention and orientation in those with spatial neglect. This suggests that augmented reality rehabilitation can be effective in treating stroke-related neglect. Additionally, the research indicates that this treatment can accurately detect neglected visual targets in stroke patients, showing promise for its use in rehabilitation.12345
Is the treatment in the trial 'Augmented Reality Rehabilitation for Stroke-Related Neglect' a promising treatment?Yes, the treatment using augmented reality for stroke-related neglect is promising. It helps detect and improve attention and orientation in stroke patients, making it a valuable tool for rehabilitation.12456
Do I have to stop taking my current medications for this trial?The trial protocol does not specify whether you need to stop taking your current medications.
Eligibility Criteria
This trial is for adults over 18 who've had a stroke and are in inpatient rehab. They must have trouble noticing things on one side (neglect), be able to hear well, respond to vibrations, speak English, and miss targets in an AR test. People with dementia, Parkinson's disease, MS, brain tumors or metal implants that affect EEGs can't join.Inclusion Criteria
I have had a recent stroke.
My hearing is normal according to a hearing test.
I am 18 years old or older.
I am currently in a rehabilitation program as an inpatient.
Exclusion Criteria
I have been diagnosed with dementia, Parkinson's, multiple sclerosis, or have a brain tumor.
I struggle to follow simple instructions most of the time.
Treatment Details
The study is testing a new tool that uses augmented reality (AR) and brainwave monitoring (EEG) to find out if someone has neglect after a stroke and help them recover. Participants will use this AR system as part of their rehabilitation therapy.
1Treatment groups
Experimental Treatment
Group I: augmented realityExperimental Treatment1 Intervention
Find a clinic near you
Research locations nearbySelect from list below to view details:
Northeastern UniversityBoston, MA
University of PittsburghPittsburgh, PA
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Who is running the clinical trial?
University of PittsburghLead Sponsor
Northeastern UniversityCollaborator
NSFCollaborator
References
The effect of virtual reality training on unilateral spatial neglect in stroke patients. [2022]To investigate the effect of virtual reality training on unilateral spatial neglect in stroke patients.
Modifying and evaluating efficacy of interactive computerized program using motion tracking technology to improve unilateral neglect in patients with chronic stroke. [2022]To modify and evaluate the efficacy of a computerized visual perception rehabilitation program using interactive motion tracking technology with unilateral neglect after chronic stroke.
Alertness Training Improves Spatial Bias and Functional Ability in Spatial Neglect. [2020]We conducted a multisite, randomized, double-blinded, controlled trial to examine the effectiveness of a digital health intervention targeting the intrinsic regulation of goal-directed alertness in patients with chronic hemispatial neglect.
Detection of Stroke-Induced Visual Neglect and Target Response Prediction Using Augmented Reality and Electroencephalography. [2023]We aim to build a system incorporating electroencephalography (EEG) and augmented reality (AR) that is capable of identifying the presence of visual spatial neglect (SN) and mapping the estimated neglected visual field. An EEG-based brain-computer interface (BCI) was used to identify those spatiospectral features that best detect participants with SN among stroke survivors using their EEG responses to ipsilesional and contralesional visual stimuli. Frontal-central delta and alpha, frontal-parietal theta, Fp1 beta, and left frontal gamma were found to be important features for neglect detection. Additionally, temporal analysis of the responses shows that the proposed model is accurate in detecting potentially neglected targets. These targets were predicted using common spatial patterns as the feature extraction algorithm and regularized discriminant analysis combined with kernel density estimation for classification. With our preliminary results, our system shows promise for reliably detecting the presence of SN and predicting visual target responses in stroke patients with SN.
Spatial Neglect Therapy With the Augmented Reality App "Negami" for Active Exploration Training: A Randomized Controlled Trial on 20 Stroke Patients With Spatial Neglect. [2023]To investigate the efficacy of the augmented reality (AR) app "Negami" as an active exploration training for the treatment of spatial neglect. Improvements of the ipsilesional attention and orientation bias (and resulting contralesional neglect) will be examined in stroke patients with spatial neglect and compared with a control group.
Head-Mounted Displays for Upper Limb Stroke Rehabilitation: A Scoping Review. [2023]Upper extremity (UE) paresis is one of the most frequent and disabling clinical consequences after stroke. Head-Mounted Displays (HMDs) are wearable virtual reality devices that seem effective in promoting the recovery of functional abilities by increasing adherence levels in this population. This scoping review is aimed at collecting available evidence on the use of HMD-based immersive virtual reality systems for UE rehabilitation treatment in stroke survivors. Four electronic bibliographic databases were consulted from inception until 18 January 2023. A total of 19 clinical trials in which HMDs were used as a clinical tool for increasing UE functioning, as a single intervention or in adjunct to other rehab treatments, were included; no restrictions were applied for UE paresis severity or stroke onset. The large majority of the clinical trials involved chronic stroke patients (15 out of 19), with a wide range of UE impairments. Overall, HMD use seemed to be well-tolerated and promising for increasing UE motor function in adult chronic stroke survivors, with benefits in subjects' arm use and independence. The possibility of executing highly realistic and task-oriented movements appears to be promising in enhancing gesture relevance, thus promoting new motor strategies in a "virtual ecological way". Across studies, we found a high heterogeneity in protocol design and a lack of reporting that prevents us drawing conclusions regarding potential subgroups of patients that could benefit more from HMD-based interventions or suggested treatment modalities.