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Protein Quality of Mung Beans for Healthy Adults

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Recruiting

Led By Dr. Glenda Courtney-Martin

Research Sponsored by The Hospital for Sick Children

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Not on any medications that could affect protein or amino acid metabolism (e.g., steroids)

Male, age 18 - 49 yrs

Must not have

Unwillingness to participate or unable to tolerate the diet

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

No Placebo-Only Group

Summary

This trial is being done to study the quality of protein in Mung beans. Researchers want to know if the amino acids in Mung beans are affected by cooking, and if the protein in Mung beans is complete. This study is important for recommendations about Mung beans as a major protein source in the diet.

Who is the study for?

This trial is for healthy men aged 18-49 with stable body weight, not on medications affecting protein metabolism like steroids. They must have no conditions such as diabetes that affect protein or amino acid metabolism and no recent significant weight changes.

What is being tested?

The study aims to determine the quality of protein from Mung beans by assessing the bioavailability of an essential amino acid called methionine. It will test cooked Mung beans alone, in stew, and combined with rice or wheat in meals.

What are the potential side effects?

Since this trial involves dietary intake of common foods without any medical interventions, side effects are minimal but may include potential food allergies or intolerance to ingredients used in the study diets.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am not taking medications that affect protein or amino acid metabolism.

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I am a man aged between 18 and 49.

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I am healthy and do not have conditions like diabetes that affect protein metabolism.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am not willing or able to follow the study's diet plan.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Metabolic availability of methionine in Mung beans

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: ArmsExperimental Treatment1 Intervention

Methionine bioavailability in Mung beans Participants will be seen initially for pre-study assessment (3 hour). They will then be studied for up to 10 times. levels of phenylalanine intake (7 Study periods). You could be expected to participate in up to 10 different sets of experiments which will take 11 weeks to 6 months. Each set of experiment consists of a 3 day period. During the first 2 days (Adaptation Days) you will be expected to consume 4 meals per day consisting of a protein liquid drink and protein freecookies and/or a Mung bean stew with or without rice or wheat, which will be provided by the investigators

0 / 4Eligibility criteria met