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Lumbar vs Extraventricular Drains for Subarachnoid Hemorrhage
N/A
Recruiting
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Patients received at the UCSD Medical Center with grade II, III, IV subarachnoid hemorrhage or patients with aneurysmal SAH with radiographic evidence.
Be older than 18 years old
Must not have
Patients under the age of 18, excluding minors from this study
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0-14 days
Awards & highlights
Summary
This trial compares two methods to drain fluid from around the brain in patients with a specific type of brain bleed. The goal is to find out which method is better at preventing complications. By reducing pressure in the skull, these methods can help improve patient recovery.
Who is the study for?
This trial is for adults at UCSD Medical Center with a grade II, III, or IV subarachnoid hemorrhage (SAH) from a ruptured aneurysm and visible blood in brain scans. It excludes anyone under 18.
What is being tested?
The study compares two methods to drain blood after SAH: extraventricular drain (EVD) and lumbar drain (LD). Patients will be randomly assigned to one of these treatments to see which better prevents vasospasm, reduces ICU stay, and lessens the need for permanent shunts.
What are the potential side effects?
Potential side effects may include discomfort at the drainage site, infection risk around the brain or spine where drains are placed, possible bleeding during insertion or removal of drains, and headaches.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have a grade II-IV subarachnoid hemorrhage or aneurysmal SAH confirmed by imaging.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am 18 years old or older.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 0-14 days
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0-14 days
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Vasopasm
Trial Design
2Treatment groups
Active Control
Group I: EVDActive Control1 Intervention
Patients will have extraventricular drain to manage CSF subarachnoid blood.
Group II: LDActive Control1 Intervention
Patients will have lumbar drain to manage CSF subarachnoid blood.
Research Highlights
Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
The primary treatments for subarachnoid hemorrhage (SAH) include the use of extraventricular drains (EVD) and lumbar drains (LD) to remove cerebrospinal fluid (CSF) and reduce the amount of subarachnoid blood. These drainage methods help to alleviate intracranial pressure and reduce the risk of vasospasm, a common and severe complication of SAH that can lead to significant neurological deficits or death.
By effectively managing the volume of subarachnoid blood, these treatments aim to prevent the narrowing of blood vessels (vasospasm) and ensure adequate cerebral perfusion, which is crucial for the recovery and prognosis of SAH patients.
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Who is running the clinical trial?
University of California, San DiegoLead Sponsor
1,157 Previous Clinical Trials
1,571,331 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have a grade II-IV subarachnoid hemorrhage or aneurysmal SAH confirmed by imaging.I am 18 years old or older.
Research Study Groups:
This trial has the following groups:- Group 1: EVD
- Group 2: LD
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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