Nicotine Pouches for Nicotine Addiction

N/A

Recruiting

Led By Dae Hee Han, PhD

Research Sponsored by University of Southern California

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Adults age 21-35 years old

Be between 18 and 65 years old

Must not have

History of stroke, seizures, high blood pressure (hypertension), heart disease/problems, lung disease/lung problems, or cardiovascular disease contraindications for nicotine

People under 21 years will be excluded to correspond with the legal age for purchasing tobacco products in the United States. Special subject populations will not be recruited

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during the 3-hour experimental session, participant will self-administer 4 nicotine pouches, each with a 5-minute administration period. there will a 40-minute inter-product rest interval.

Summary

"This trial aims to study the effects of different nicotine concentrations and pH levels in modern tobacco-free oral nicotine pouches on the appeal and sensory attributes among younger adults who use these products. The research will provide

Who is the study for?

This trial is for young adults who have used nicotine pouches and e-cigarettes or combustible cigarettes in the past 30 days. Participants should not be looking to quit nicotine use. The study specifically targets current dual users of these products.

What is being tested?

The study is testing how different levels of nicotine concentration (3 mg vs 6 mg) and pH values (8.5 or higher vs lower than 8.5) in nicotine pouches affect their appeal and sensory experience among users, using a double-blind randomized design.

What are the potential side effects?

While specific side effects are not detailed here, typical risks may include throat irritation, increased heart rate, nausea, addiction potential, and other symptoms associated with nicotine use.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 21 and 35 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have a history of stroke, seizures, high blood pressure, heart or lung problems.

Select...

I am 21 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during the 3-hour experimental session, participant will self-administer 4 nicotine pouches, each with a 5-minute administration period. there will a 40-minute inter-product rest interval.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during the 3-hour experimental session, participant will self-administer 4 nicotine pouches, each with a 5-minute administration period. there will a 40-minute inter-product rest interval.

This trial's timeline: 3 weeks for screening, Varies for treatment, and during the 3-hour experimental session, participant will self-administer 4 nicotine pouches, each with a 5-minute administration period. there will a 40-minute inter-product rest interval. for reporting.