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Almonds for Acne

N/A
Recruiting
Research Sponsored by Integrative Skin Science and Research
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Subjects 15 years of age until 45 years of age
Be younger than 65 years old
Must not have
The presence of severe acne as noted by the investigator global assessment
Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 20 weeks

Summary

This trial will study the effects of almond supplementation on acne and gut health.

Who is the study for?
This trial is for people aged 15-45 with mild to moderate acne who have been on a stable acne treatment for at least 4 weeks. It's not suitable for those with nut allergies, recent changes in hormonal contraception, heavy past tobacco use, or those using certain strong acne medications.
What is being tested?
The study is testing if eating whole almonds can improve acne and gut health compared to a non-nut snack. Participants will be given either almonds or the control snack to see which has better effects on their skin and digestion.
What are the potential side effects?
Since this trial involves food supplementation (almonds), side effects may include digestive discomfort or allergic reactions in individuals sensitive to nuts. Other specific side effects will depend on individual tolerances.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 15 and 45 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have been diagnosed with severe acne by a healthcare professional.
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I currently smoke or have smoked a lot in the past.
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I am willing to stop using topical antibiotics and benzoyl peroxide before joining.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~20 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 20 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Total lesion count
Secondary study objectives
Gut microbiome assessment
Inflammatory lesion count
Investigator global assessment (IGA) of acne
+4 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: AlmondsExperimental Treatment1 Intervention
Daily consumption of almonds.
Group II: Control SnackPlacebo Group1 Intervention
Daily non-nut snack will be consumed.

Find a Location

Who is running the clinical trial?

Integrative Skin Science and ResearchLead Sponsor
32 Previous Clinical Trials
1,914 Total Patients Enrolled
3 Trials studying Acne
202 Patients Enrolled for Acne
Almond Board of CaliforniaOTHER
34 Previous Clinical Trials
2,161 Total Patients Enrolled

Media Library

Almond Supplementation (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05269641 — N/A
Acne Research Study Groups: Control Snack, Almonds
Acne Clinical Trial 2023: Almond Supplementation Highlights & Side Effects. Trial Name: NCT05269641 — N/A
Almond Supplementation (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05269641 — N/A
~16 spots leftby Nov 2025