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Behavioral Intervention

Alternatives to Opioids for Pain After Tooth Extraction (ADOPT Trial)

N/A

Waitlist Available

Led By Douglas R Oyler, PharmD

Research Sponsored by Douglas Oyler

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patient must be aged 12-25 at the time of tooth extraction

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up same calendar date as dental extraction. electronic health records will be extracted for the duration of the 4-year study period.

Awards & highlights

No Placebo-Only Group

Summary

"This trial aims to test a new intervention for oral surgeons who remove teeth to see if it can reduce opioid prescriptions to adolescents and young adults after the procedure. The study will also evaluate if the intervention changes

Who is the study for?

This trial is for adolescents and young adults who are having teeth removed. Oral surgeons participating will need to attend an educational session, provide specific pain medications, and complete surveys. Patients must take a survey about their pain and medication use post-extraction.

What is being tested?

The study tests if a three-part intervention can cut down opioid prescriptions after tooth removal compared to usual care. It includes education for oral surgeons, special patient instructions, and blister packs of non-opioid pain medicine.

What are the potential side effects?

Since the focus is on reducing opioid use by providing alternatives like acetaminophen or ibuprofen, side effects may include typical reactions to these drugs such as stomach upset or mild allergic responses.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 12 and 25 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ same calendar date as dental extraction. electronic health records will be extracted for the duration of the 4-year study period.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~same calendar date as dental extraction. electronic health records will be extracted for the duration of the 4-year study period.

This trial's timeline: 3 weeks for screening, Varies for treatment, and same calendar date as dental extraction. electronic health records will be extracted for the duration of the 4-year study period. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Odds of post-extraction opioid prescription to adolescent/young adults after tooth extraction

Secondary study objectives

(Change in) intervention appropriateness

(Change in) intervention feasibility

(Change in) opioid prescribing appropriateness

+4 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Intervention conditionExperimental Treatment1 Intervention

1. Academic detailing (45 to 60-minute session), plus 2. Provision of standardized patient post-extraction instructions for distribution, plus 3. Provision of blister-packaged acetaminophen and ibuprofen at recommended standard doses for distribution to to adolescent/young adult patients after tooth extraction in the course of clinical practice

Group II: Control conditionActive Control1 Intervention

Usual practice

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Multicomponent intervention

2014

Completed Phase 3

~7990

0 / 1Eligibility criteria met