Fast Track Intervention for Conduct Disorder

Recruiting in Palo Alto (17 mi)

Overseen by Kenneth A Dodge, PhD

Age: < 18

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Duke University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The primary aim of this project is to evaluate the effects of a comprehensive intervention to prevent severe and chronic conduct problems in a sample of children selected as high-risk when they first entered school. It is hypothesized that the intervention will have positive effects on proximal child behavior in middle school, and high school affecting long-term adolescent outcomes such as conduct disorder, juvenile delinquency, school dropout, substance use, teen pregnancy, relational competence with peers, romantic partners and parents, education and employment and social and community integration.

Research Team

Ellen E Pinderhughes, PhD

Principal Investigator

Tufts University

John E Lochman, PhD

Principal Investigator

University of Alabama at Birmingham

Robert J McMahon, PhD

Principal Investigator

Simon Fraser University

Daniel M Crowley, PhD

Principal Investigator

Penn State University

Jennifer Lansford, PhD

Principal Investigator

Duke University

Karen L Bierman, PhD

Principal Investigator

Penn State University

Mark T Greenberg, PhD

Principal Investigator

Penn State University

Kenneth A Dodge, PhD

Principal Investigator

Duke University

Eligibility Criteria

This trial is for first graders in public schools at 4 study sites, identified as high-risk for severe conduct problems. Children must score in the top 40% on the TOCA-R assessment. Those older than first grade are not eligible.

Inclusion Criteria

Must be in public schools in 4 study sites

I am currently in the 1st grade.

Exclusion Criteria

I am in kindergarten or 1st grade.

Could not score in the top 40% on the TOCA-R

Treatment Details

Interventions

• Fast Track (Behavioral Intervention)

Trial Overview The 'Fast Track' program aims to prevent chronic conduct issues among high-risk children. It will be tested if this intervention positively impacts behavior and prevents negative outcomes like delinquency or school dropout.

Participant Groups

Group I: Fast Track Eligible Experimental Treatment 1 Intervention

Participants in the Experimental group received the "Fast Track" intervention. Intervention included school-based curriculum attended by high-risk children, parents, program staff, and occasionally teachers, home visiting, the the in-class PATHS prevention program.

Group II: Control Group Active Control 1 Intervention

Participants in the Control group were not eligible to receive the Fast Track intervention. These children received other services as usual, and served as the randomized comparison group for examining Fast Track program impacts

Who Is Running the Clinical Trial?

Duke University

Lead Sponsor

Trials

2,495

Recruited

5,912,000+

Mary E. Klotman

Duke University

Chief Executive Officer since 2017

MD from Duke University School of Medicine

Michelle McMurry-Heath

Duke University

Chief Medical Officer since 2020

MD from Duke University School of Medicine

National Institute of Mental Health (NIMH)

Collaborator

Trials

3,007

Recruited

2,852,000+

Dr. Joshua A. Gordon

National Institute of Mental Health (NIMH)

Chief Executive Officer since 2016

MD, PhD

Dr. Shelli Avenevoli

National Institute of Mental Health (NIMH)

Chief Medical Officer

PhD

National Institute on Drug Abuse (NIDA)

Collaborator

Trials

2,658

Recruited

3,409,000+

Dr. Nora Volkow

National Institute on Drug Abuse (NIDA)

Chief Executive Officer since 2003

MD from National Autonomous University of Mexico

Dr. Nora Volkow

National Institute on Drug Abuse (NIDA)

Chief Medical Officer since 2003

MD from National Autonomous University of Mexico

U.S. Department of Education

Collaborator

Trials

87

Recruited

54,500+

Linda McMahon

U.S. Department of Education

Secretary of Education

Bachelor's degree in Business Administration from East Carolina University

Dr. Patrizia Cavazzoni

U.S. Department of Education

Chief Medical Officer

MD from Harvard Medical School

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborator

Trials

2,103

Recruited

2,760,000+

Dr. Diana W. Bianchi

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Chief Executive Officer since 2016

MD from Stanford University

Dr. Alison Cernich

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Chief Medical Officer since 2020

PhD in Clinical Psychology from University of Maryland