Speech Therapy + tDCS for Aphasia

Palo Alto (17 mi)

Overseen byMaya Henry, PhD

Age: Any Age

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Waitlist Available

Sponsor: University of Texas at Austin

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial aims to help people with primary progressive aphasia (PPA) by combining home-based brain stimulation with online speech therapy. The brain stimulation uses a gentle electrical current to boost the effects of speech therapy, which may improve communication skills and quality of life for those affected by PPA.

Eligibility Criteria

This trial is for adults with Primary Progressive Aphasia who can think clearly enough (score of 20+ on a mental state exam), see and hear well (with aids if needed), undergo an MRI, have internet access, and a partner to help them through the study. It's not for those with other neurological issues, history of stroke/epilepsy/severe brain injury, or contraindications for tDCS/MRI.

Inclusion Criteria

My mental state score is 20 or higher.

I have been diagnosed with primary progressive aphasia.

I have been diagnosed with a specific type of primary progressive aphasia.

I am willing and able to have an MRI scan of my brain.

Exclusion Criteria

I don't have a history of seizures, head injuries, severe migraines, metal implants in my head, chronic skin problems, or a pacemaker. I am not pregnant.

My speech and language issues are due to a different neurological condition.

I have had a stroke, epilepsy, or significant brain injury.

Treatment Details

The trial tests whether home-based brain stimulation paired with speech-language therapy via video call helps people with different types of PPA. Participants will receive either real or sham brain stimulation while engaging in language exercises designed to improve communication.

2Treatment groups

Experimental Treatment

Group I: RS-VISTAExperimental Treatment3 Interventions

Group II: RS-LRTExperimental Treatment3 Interventions