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Speech-Language Therapy for Primary Progressive Aphasia

N/A

Recruiting

Led By Stephanie M Grasso, Ph.D

Research Sponsored by University of Texas at Austin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Meets diagnostic criteria for Primary Progressive Aphasia (PPA; Gorno-Tempini et al., 2011)

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up pre-phase 1, post-phase1/pre-phase 2 (4.5 weeks from treatment onset), post-phase 2 (9 weeks from treatment onset), 6 months and 1 year post-treatment

Awards & highlights

No Placebo-Only Group

Summary

This trial seeks to study how tailored speech-language interventions help bilingual individuals with PPA. Researchers will evaluate effects of treatment, language use, and brain scans to determine best approach.

Who is the study for?

This trial is for bilingual individuals who speak Spanish and Catalan or Spanish and English, diagnosed with Primary Progressive Aphasia (PPA). Participants must have a certain level of cognitive function as measured by the Mini-Mental State Examination. Those with other central nervous system issues, significant sensory impairments, or prominent non-speech-language impairments cannot join.

What is being tested?

The study tests two speech-language interventions: Video-Implemented Script Training for Aphasia (VISTA) and Lexical Retrieval Training (LRT), tailored for bilingual speakers with PPA. It aims to understand how bilingualism affects treatment response in PPA over time, including follow-ups at 6 and 12 months post-treatment.

What are the potential side effects?

Since this trial involves speech-language therapy rather than medication, traditional side effects are not expected. However, participants may experience fatigue or frustration during the intervention sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with Primary Progressive Aphasia.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ pre-phase 1, post-phase1/pre-phase 2 (4.5 weeks from treatment onset), post-phase 2 (9 weeks from treatment onset), 6 months and 1 year post-treatment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~pre-phase 1, post-phase1/pre-phase 2 (4.5 weeks from treatment onset), post-phase 2 (9 weeks from treatment onset), 6 months and 1 year post-treatment

This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-phase 1, post-phase1/pre-phase 2 (4.5 weeks from treatment onset), post-phase 2 (9 weeks from treatment onset), 6 months and 1 year post-treatment for reporting.