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Breathing Training for Bronchiectasis

N/A

Recruiting

Led By Bryan Taylor, PhD

Research Sponsored by Mayo Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Presence of advanced heart failure.

Current use of antibiotics.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 8 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial looks into using breathing and muscle exercises to improve exercise ability, lung function, and general health for people with non-CFB.

Who is the study for?

This trial is for Mayo Clinic patients with non-cystic fibrosis bronchiectasis (non-CFB), who can consent to participate. They should be stable, without exacerbations or changes in therapy for three weeks and not have heart failure, major diseases, neurological conditions, orthopedic issues affecting exercise, recent pulmonary rehab participation or current antibiotic use.

What is being tested?

The study tests a home-based breathing training program supported by health coaches. It aims to see if this LungTrainers Pulmonary Rehabilitation regime improves exercise capacity, lung and respiratory muscle function, and overall clinical status in individuals with non-CFB.

What are the potential side effects?

While the trial description does not specify side effects directly related to the interventions being studied (LungTrainers regime), typical concerns may include muscle soreness or fatigue from new exercises.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

My condition is advanced heart failure.

Select...

I am currently taking antibiotics.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 8 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 8 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 8 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in peak oxygen uptake during maximal incremental exercise test

Change in six-minute walk test distance

Secondary study objectives

Change in Dartmouth COOP Functional Assessment Charts

Change in Modified Medical Research Council Dyspnea Scale (mMRC)

Change in St. George's Respiratory Questionnaire (SGRQ)

+10 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Home-based specific breathing and respiratory muscle training groupExperimental Treatment2 Interventions

In addition standard of care pulmonary rehabilitation, subjects will participate in an 8-week home-based specific breathing and respiratory muscle training via the LungTrainers Pulmonary Rehabilitation regime (LT-PR).

Group II: Control group of standard physician directed careActive Control1 Intervention

Subjects will receive pulmonary rehabilitation via standard physician directed care (i.e., 'normal care').

0 / 2Eligibility criteria met