Laser Resurfacing for Skin Rejuvenation

Overseen by Jeffrey Travers, MD, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Wright State University

No Placebo Group

Approved in 3 Jurisdictions

Trial Summary

What is the purpose of this trial?

It has shown that laser wounding of geriatric skin protects it against skin cancer. The purpose of this study is to determine the origin of cells called fibroblasts which are present after treatment with Fractionated Laser Resurfacing (FLR). These cells restore a youth-like ultraviolet B (UVB) response, but where they come from is currently unknown. The study recruits subjects who are scheduled to undergo abdominoplasties to investigate the origin of those cells stimulated by laser treatment.

Research Team

Jeffrey Travers, MD, PhD

Principal Investigator

Wright State University

Eligibility Criteria

This trial is for individuals scheduled for abdominoplasty who may benefit from Fractionated Laser Resurfacing (FLR) to potentially protect against skin cancer. The study focuses on understanding how FLR treatment rejuvenates the skin by examining fibroblasts, cells that help repair damaged skin.

Inclusion Criteria

I understand the procedures and risks involved.

I am 18 years old or older.

I am planning to have a tummy tuck surgery.

Exclusion Criteria

Existing tattoos on the abdomen that are so extensive that they could interfere with the study

My diabetes is not well-controlled.

Pregnant or nursing

Treatment Details

Interventions

• Fractionated Laser Resurfacing (Procedure)

Trial Overview The trial investigates the origin of fibroblasts after Fractionated Laser Resurfacing treatment in patients undergoing abdominoplasty. It aims to understand how these cells contribute to a youthful UVB response and possibly prevent skin cancer.

Participant Groups

Group I: Fractionated Laser Resurfacing Experimental Treatment 1 Intervention

At 14 days prior to scheduled surgery a 5x5cm square on the left abdomen within the region of skin to be excised and treated with fractionated laser resurfacing. Then at 7 days prior to scheduled surgery a 5 cm diameter circle on the right abdomen within the region of skin to be excised, at least 10 cm away from the square, is treated with fractionated laser resurfacing.

Fractionated Laser Resurfacing is already approved in Canada for the following indications:

Approved in Canada as Fractional Laser Resurfacing for:

• Wrinkles
• Scars
• Sun damage
• Melasma
• Actinic keratosis
• Non-melanoma skin cancers

Who Is Running the Clinical Trial?

Wright State University

Lead Sponsor

Trials

47

Recruited

55,300+