Trial Summary
What is the purpose of this trial?
This trial studies how well using ultrasound and a needle to take lung tissue samples after an imaging scan works in diagnosing early-stage lung cancer. It aims to improve the accuracy of determining the cancer stage in patients being considered for a specific type of radiation therapy.
Research Team
GA
George Eapen, MD
Principal Investigator
M.D. Anderson Cancer Center
Eligibility Criteria
This trial is for adults over 18 with early-stage non-small cell lung cancer (Stage I or IIa), who haven't had chemotherapy or radiotherapy for this cancer, and are being considered for a precise type of radiation therapy called SBRT. They must have had a PET/CT scan within the last 40 days and provided written consent. Cancer survivors can join if they've been free from active disease for at least five years.Inclusion Criteria
Patient or the patient's legally authorized representative must provide written informed consent prior to registration and any study-related procedures
I am being considered for a type of radiation therapy called SBRT.
My lung cancer is in the early stages (Stage I or IIa).
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Exclusion Criteria
You are planning to get treatment at a different hospital or clinic.
I am already scheduled for standard cancer treatments other than at disease progression.
My cancer is a type of well-differentiated neuroendocrine tumor.
See 1 more
Treatment Details
Interventions
- Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) (Procedure)
Trial OverviewThe study is testing how well EBUS-TBNA works in diagnosing patients after they've had a PET/CT scan. It aims to improve accuracy in detecting early-stage lung cancer among those evaluated for stereotactic body radiation therapy.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: EBUS-TBNAExperimental Treatment1 Intervention
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) performed after PET/CT, and before participant receives stereotactic body radiation therapy (SBRT). EBUS-TBNA results compared with the results of PET/CT.
A conventional flexible bronchoscopy performed to examine the tracheobronchial tree, followed by a systematic examination of the accessible intra-thoracic lymph nodes using a linear array ultrasound bronchoscope.
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
Trials
3,107
Recruited
1,813,000+
Dr. Peter WT Pisters
M.D. Anderson Cancer Center
Chief Executive Officer since 2017
MD from University of Western Ontario
Dr. Jeffrey E. Lee
M.D. Anderson Cancer Center
Chief Medical Officer
MD from Stanford University School of Medicine