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Role of Aging and Individual Variation in Exercise Training Responsiveness (STRRIDE IV Trial)

Durham, NC
N/A
Waitlist Available
Led By Leanna M Ross, PhD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, early-intervention (~6 weeks), and post-intervention (~24 weeks)
Awards & highlights
No Placebo-Only Group

Summary

The primary purpose of this study is to assess the effects of aging on markers of physical reserve and exercise-induced adaptations in resilience in older adults who completed a structured exercise program within the last 15 years (Parent trial: STRRIDE-PD; NCT00962962). This feasibility pilot study will enroll up to 8 participants to complete a 6-month aerobic exercise intervention.

See full description
Eligible Conditions
  • Cardiovascular Disease
  • Insulin Resistance
  • Incretin Hormones in Polycystic Ovary Syndrome
  • Obesity
  • Prediabetes

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, early-intervention (~6 weeks), and post-intervention (~24 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, early-intervention (~6 weeks), and post-intervention (~24 weeks) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Cardiorespiratory Fitness
Insulin Sensitivity
Secondary study objectives
Body Composition
Health-Related Quality of Life
Metabolic Syndrome Z-Score
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: Low Amount/Moderate Intensity (Low/Mod)Experimental Treatment1 Intervention
Six months of low amount/moderate intensity aerobic exercise
Group II: High Amount/Vigorous Intensity (High/Vig)Experimental Treatment1 Intervention
Six months of high amount/vigorous intensity aerobic exercise
Group III: High Amount/Moderate Intensity (High/Mod)Experimental Treatment1 Intervention
Six months of high amount/moderate intensity aerobic exercise

Find a Location

Closest Location:Duke Center for Living· Durham, NC

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,494 Previous Clinical Trials
5,912,374 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,838 Previous Clinical Trials
28,145,073 Total Patients Enrolled
National Institutes of Health (NIH)NIH
2,894 Previous Clinical Trials
8,052,786 Total Patients Enrolled
Leanna M Ross, PhDPrincipal InvestigatorDuke University
~5 spots leftby Feb 2026
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