Load Modulation for Cerebral Palsy

Age: < 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Northwestern University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to investigate lower limb impairments in children with bilateral cerebral palsy during stepping tasks.

Research Team

Eligibility Criteria

This trial is for children and teenagers aged 5 to 19 who can step up independently, with or without help from devices. It's specifically for those with bilateral cerebral palsy where legs are more affected than arms, but also includes typically developing individuals without movement-affecting conditions.

Inclusion Criteria

I either have no medical conditions affecting movement or have cerebral palsy with my legs more affected than my arms.

I am between 5 and 19 years old.

I can step up on my own, with or without help from devices.

Exclusion Criteria

I have trouble understanding or following instructions.

Comorbidities that would make participation unsafe.

I had surgery on my leg or foot in the last year.

Treatment Details

Interventions

• Load Modulation (Other)

Trial Overview The study is exploring how load modulation affects stepping tasks in participants with bilateral cerebral palsy. Researchers want to understand the lower limb impairments during these activities.

Participant Groups

Group I: load modulation Experimental Treatment 1 Intervention

Participants will experience different body weight loading conditions - with body weight added by a weighted vest or removed using the ZeroG overhead harness.

Who Is Running the Clinical Trial?

Northwestern University

Lead Sponsor

Trials

1,674

Recruited

989,000+

Dr. Jeffrey Sherman

Northwestern University

Chief Medical Officer

MD from Northwestern University

Dr. Alicia Löffler

Northwestern University

Chief Executive Officer since 2010

PhD from the University of Massachusetts at Amherst, post-doctoral training at Caltech