← Back to Search

Memory Training for Mild Cognitive Impairment

N/A

Recruiting

Led By Nancy Chiaravalloti

Research Sponsored by Kessler Foundation

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

60 or older.

Must not have

Prior stroke or neurological injury/disease (i.e. traumatic brain injury, Multiple Sclerosis, or Stroke).

Benzodiazepines and steroid use.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up four points in time: pre-treatment, immediately following treatment, and 6- and 18- months after treatment is completed

Summary

This trial is testing whether a memory retraining program can help people with mild cognitive impairment (MCI). MCI is a common cognitive deficit that can negatively impact everyday life. The trial will test the effects of the memory retraining program on cognitive function and everyday life.

Who is the study for?

This trial is for individuals aged 60 or older who have been diagnosed with amnestic Mild Cognitive Impairment (MCI) and are fluent in English. It's not suitable for those with a history of stroke, neurological injuries/diseases, significant alcohol/drug abuse requiring inpatient treatment, use of benzodiazepines/steroids, or major psychiatric conditions like bipolar disorder or schizophrenia.

What is being tested?

The study tests the effectiveness of memory retraining exercises compared to placebo control exercises on improving learning and memory in people with MCI. Participants will be randomly assigned to one of the two groups and assessed through neuropsychological tests, daily functioning questionnaires, and optional functional neuroimaging before and after treatment.

What are the potential side effects?

Since this trial involves cognitive exercises rather than medication, traditional side effects are not expected. However, participants may experience fatigue or frustration during testing sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 60 years old or older.

Select...

I am 60 years old or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have had a stroke or a neurological condition like MS.

Select...

I am currently using benzodiazepines or steroids.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ four points in time: pre-treatment, immediately following treatment, and 6- and 18- months after treatment is completed

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~four points in time: pre-treatment, immediately following treatment, and 6- and 18- months after treatment is completed

This trial's timeline: 3 weeks for screening, Varies for treatment, and four points in time: pre-treatment, immediately following treatment, and 6- and 18- months after treatment is completed for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Participation in everyday life

Verbal list learning

Secondary study objectives

Functional memory

Functional neuroimaging

Self-reported anxiety

+4 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Experimental GroupExperimental Treatment1 Intervention

The experimental group will receive memory retraining exercises administered on a laptop computer twice a week for five weeks (10 training sessions).

Group II: Placebo Control GroupPlacebo Group1 Intervention

The placebo control group will receive placebo memory exercises administered on a laptop computer twice a week for five weeks (10 placebo control sessions).

0 / 4Eligibility criteria met