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Behavioral Intervention

RRE App for Preventing Teen Depression

N/A
Recruiting
Led By Chieh Li, EdD
Research Sponsored by Northeastern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5-7 minutes
Awards & highlights
No Placebo-Only Group

Summary

This trial tests a mobile app called RRE to help Chinese American teenagers feel better mentally. The app provides relaxation exercises and stress management activities with guidance from a virtual companion. Participants can earn rewards for using the app.

Who is the study for?
This trial is for Chinese American adolescents aged 14-18, who can read at a sixth-grade level or higher. It's not suitable for those with severe depression or anxiety needing more treatment than the app provides, or other mental disorders.
What is being tested?
The study tests if a mobile app called Relax, Reflect, and Empower (RRE) can improve psychological well-being and reduce depressive symptoms in participants compared to a control group receiving wellness check-in texts over three months.
What are the potential side effects?
Since this intervention involves using an application designed to promote wellbeing, there are no direct physical side effects expected. However, users may experience varying emotional responses based on their engagement with the content.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5-7 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5-7 minutes for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Patient Health Questionnaire 9 (PHQ-9)
Secondary study objectives
Coping self-efficacy scale (CSES)
Flourishing Scale

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Relax, Reflect, and Empower applicationExperimental Treatment1 Intervention
Participants in the RRE group will select an Avatar from a pool of 20 Avatars as their companion over the 3 months. The Avatar wellness check-in in the RRE group includes a daily brief check-in of 5-minute/day (4 days/week), and a weekly full wellness check-in of 15 minutes/week for 3 months. The daily brief check-in includes a wellbeing and mood check and a 3-minute relaxation meditation. The weekly full wellness check-in includes reflection activities in addition to the daily check-in activities.
Group II: Daily check-in text messagesActive Control1 Intervention
Participants will receive a wellness check-in text message 5 days/week \[4 daily wellness check-in (2-3 minutes/day) +1 weekly wellness check-in (4-5 minutes/week)\] for 3 months.

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.
Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
Common treatments for depression include pharmacotherapy, such as antidepressants, and psychological therapies like Cognitive Behavioral Therapy (CBT) and Mindfulness-Based Cognitive Therapy (MBCT). Antidepressants work by altering neurotransmitter levels in the brain, such as serotonin and norepinephrine, to improve mood and emotional state. CBT helps patients identify and change negative thought patterns and behaviors, while MBCT combines cognitive therapy with mindfulness strategies to prevent relapse. The RRE Mobile Health Application, which promotes psychological wellbeing and reduces depressive symptoms through culturally sensitive content and engagement, likely incorporates elements of CBT and mindfulness. Understanding these mechanisms is crucial for depression patients as it helps them comprehend how treatments can alter their mental state, providing a sense of control and encouraging adherence to therapy.
Psychological therapies for anxiety and depression in children and adolescents with long-term physical conditions.Electronic behavioral interventions for headache: a systematic review.

Find a Location

Who is running the clinical trial?

Northeastern UniversityLead Sponsor
99 Previous Clinical Trials
70,966 Total Patients Enrolled
3 Trials studying Depression
124 Patients Enrolled for Depression
Florida A&M UniversityOTHER
7 Previous Clinical Trials
4,945 Total Patients Enrolled
Florida State UniversityOTHER
224 Previous Clinical Trials
36,625 Total Patients Enrolled
7 Trials studying Depression
1,377 Patients Enrolled for Depression
Chieh Li, EdDPrincipal InvestigatorNortheastern University
Huijun Li, PhDPrincipal InvestigatorFlorida A&M University
Shengli Dong, PhDPrincipal InvestigatorFlorida State University

Media Library

Relax, Reflect, Empower-RRE (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05921201 — N/A
Depression Research Study Groups: Daily check-in text messages, Relax, Reflect, and Empower application
Depression Clinical Trial 2023: Relax, Reflect, Empower-RRE Highlights & Side Effects. Trial Name: NCT05921201 — N/A
Relax, Reflect, Empower-RRE (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05921201 — N/A
~11 spots leftby Feb 2025