← Back to Search

Anti-microbial

Bleach Bath Treatment of Adults With Atopic Dermatitis

N/A
Waitlist Available
Led By Lisa Beck, MD
Research Sponsored by University of Rochester
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline after 12 weeks of bleach baths
Awards & highlights
All Individual Drugs Already Approved
No Placebo-Only Group

Summary

This is pilot, mechanistic study to address whether bleach baths given to adult subjects with atopic dermatitis or eczema, who are colonized with the bacteria Staphylococcus aureus, will significantly alter their skin microbiome and in so doing improve their skin barrier, diminish expression of inflammatory proteins in the skin and improve itch. To answer these questions the investigators will perform a 3-month, pilot, investigator-initiated, single-center, open-label clinical study. This study will allow us to test the following hypothesis: 1) that bleach baths will normalize skin barrier function, 2) that bleach baths will diminish the local inflammatory response in the skin, and 3) that bleach baths will improve validated measures of itch (also called pruritus).

Eligible Conditions
  • Atopic Dermatitis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline after 12 weeks of bleach baths
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline after 12 weeks of bleach baths for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Noninvasive barrier measurement called Transepidermal Water Loss (TEWL) done before and after repeated tape stripping
Secondary study objectives
Itch - 5D pruritus scale
Skin bacterial diversity
Skin permeability
+2 more

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Dilute bleach bathExperimental Treatment1 Intervention
Subjects will take a diluted bleach bath (0.005% Sodium hypochlorite) for 5-10 minutes twice a week for 12 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Hypochlorite
FDA approved

Find a Location

Who is running the clinical trial?

University of RochesterLead Sponsor
872 Previous Clinical Trials
550,039 Total Patients Enrolled
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NIH
502 Previous Clinical Trials
1,089,960 Total Patients Enrolled
National Eczema AssociationUNKNOWN
1 Previous Clinical Trials
151 Total Patients Enrolled
Lisa Beck, MDPrincipal InvestigatorDepartment of Dermatology University of Rochester
4 Previous Clinical Trials
4,878 Total Patients Enrolled
~5 spots leftby Jan 2026