~5 spots leftby Apr 2026

Bleach Bath Treatment of Adults With Atopic Dermatitis

Recruiting in Palo Alto (17 mi)
LB
Overseen byLisa Beck, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of Rochester
No Placebo Group

Trial Summary

What is the purpose of this trial?

This is pilot, mechanistic study to address whether bleach baths given to adult subjects with atopic dermatitis or eczema, who are colonized with the bacteria Staphylococcus aureus, will significantly alter their skin microbiome and in so doing improve their skin barrier, diminish expression of inflammatory proteins in the skin and improve itch. To answer these questions the investigators will perform a 3-month, pilot, investigator-initiated, single-center, open-label clinical study. This study will allow us to test the following hypothesis: 1) that bleach baths will normalize skin barrier function, 2) that bleach baths will diminish the local inflammatory response in the skin, and 3) that bleach baths will improve validated measures of itch (also called pruritus).

Research Team

LB

Lisa Beck, MD

Principal Investigator

Department of Dermatology University of Rochester

Eligibility Criteria

Inclusion Criteria

Moderate to severe Atopic dermatitis: Eczema Area and Severity Index (EASI) score ≥ 10.
Skin culture positive for Staphylococcus aureus
Must have active skin disease on the day of enrollment.

Treatment Details

Interventions

  • Bleach Bath (Sodium Hypochlorite) (Anti-microbial)
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Dilute bleach bathExperimental Treatment1 Intervention
Subjects will take a diluted bleach bath (0.005% Sodium hypochlorite) for 5-10 minutes twice a week for 12 weeks.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Rochester

Lead Sponsor

Trials
883
Recruited
555,000+
Kevin Koch profile image

Kevin Koch

University of Rochester

Chief Executive Officer since 2020

PhD in Organic Chemistry from the University of Rochester

Brian Druker profile image

Brian Druker

University of Rochester

Chief Medical Officer since 2015

MD from Harvard Medical School

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborator

Trials
508
Recruited
1,090,000+
Dr. Lindsey A. Criswell profile image

Dr. Lindsey A. Criswell

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Director since 2021

MD, MPH, DSc

Dr. Robert Colbert profile image

Dr. Robert Colbert

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Clinical Director since 2014

MD

National Eczema Association

Collaborator

Trials
2
Recruited
210+