Bleach Bath Treatment of Adults With Atopic Dermatitis
Palo Alto (17 mi)Overseen byLisa Beck, MD
Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: N/A
Waitlist Available
Sponsor: University of Rochester
No Placebo Group
Trial Summary
What is the purpose of this trial?This is pilot, mechanistic study to address whether bleach baths given to adult subjects with atopic dermatitis or eczema, who are colonized with the bacteria Staphylococcus aureus, will significantly alter their skin microbiome and in so doing improve their skin barrier, diminish expression of inflammatory proteins in the skin and improve itch. To answer these questions the investigators will perform a 3-month, pilot, investigator-initiated, single-center, open-label clinical study. This study will allow us to test the following hypothesis: 1) that bleach baths will normalize skin barrier function, 2) that bleach baths will diminish the local inflammatory response in the skin, and 3) that bleach baths will improve validated measures of itch (also called pruritus).
Eligibility Criteria
Treatment Details
1Treatment groups
Experimental Treatment
Group I: Dilute bleach bathExperimental Treatment1 Intervention
Subjects will take a diluted bleach bath (0.005% Sodium hypochlorite) for 5-10 minutes twice a week for 12 weeks.
Find a clinic near you
Research locations nearbySelect from list below to view details:
University of Rochester Medical CenterRochester, NY
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Who is running the clinical trial?
University of RochesterLead Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Collaborator
National Eczema AssociationCollaborator