PrimaColl + Whey Protein for Collagen Synthesis Enhancement

Overseen by Keith Baar, PhD

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of California, Davis

Trial Summary

What is the purpose of this trial?

This trial tests if taking different types of collagen or protein supplements with vitamin C helps the body make more collagen. Healthy young adults aged 18-30 will take these supplements and do exercises. The study will measure how much new collagen is made to see if these supplements can help reduce injuries to ligaments, tendons, and bones. Collagen peptide supplements have been shown to improve body composition and strength when paired with resistance training.

Research Team

Keith Baar, PhD

Principal Investigator

UC Davis

Eligibility Criteria

This trial is for healthy, active men and women with a normal weight (BMI between 18-25). Participants should not have dietary restrictions affected by supplements, more than three muscle or bone injuries in the past year, or be on medication that could interfere with the study.

Inclusion Criteria

You are a healthy and physically active male or female.

You have a healthy weight, meaning your body mass index (BMI) is between 18 and 25 kg/m2.

Exclusion Criteria

You have any health or diet restrictions that would prevent you from following the supplement plan.

You have had more than three injuries to your bones, muscles, or joints in the past year.

You are currently taking medication that could affect the study results.

Treatment Details

Interventions

• Hydrolized Collagen (Dietary Supplement)
• Placebo (Dietary Supplement)
• PrimaColl (Dietary Supplement)
• Whey protein (Dietary Supplement)

Trial Overview The study tests how different supplements affect collagen production when taken before exercise. It compares vitamin C enriched hydrolyzed collagen, PrimaColl™, whey protein, and a placebo over a day with repeated doses and jump rope exercises.

Participant Groups

Group I: Whey Protein Experimental Treatment 1 Intervention

This arm will be given whey protein (20g with 50mg vitamin C)

Group II: PrimaColl Experimental Treatment 1 Intervention

This arm will be given PrimaColl, a vegan collagen supplementation (20g with 50mg vitamin C)

Group III: Hydrolized Collagen Experimental Treatment 1 Intervention

This arm will be given Hydrolized Collagen (20g with 50mg vitamin C)

Group IV: Placebo Placebo Group 1 Intervention

This arm will be given a placebo (20g maltodextrin with 50mg vitamin C)

Who Is Running the Clinical Trial?

University of California, Davis

Lead Sponsor

Trials

958

Recruited

4,816,000+

Rakesh Dixit

University of California, Davis

Chief Executive Officer since 2024

PhD in Biochemistry and Molecular Biology from the University of California, Davis

Suresh Mahabhashyam

University of California, Davis

Chief Medical Officer since 2020

MD from Bangalore Medical College

Geltor

Collaborator

Trials

1

Recruited

20+