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Motor Memory Assessment for Post-COVID Syndrome

N/A

Recruiting

Led By Leonardo G Cohen, M.D.

Research Sponsored by National Institute of Neurological Disorders and Stroke (NINDS)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Deny active infection with COVID-19, or ongoing symptoms following COVID-19 infection

Enrolled in the screening phase of Protocol 000089 Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health in the post-COVID convalescence arm (i.e. reports having started recovery from an acute COVID- 19 infection within past six month and is able to provide documentation of a positive COVID-19 PCR or antibody test)

Must not have

Fever, respiratory symptoms or diagnosis of COVID-19 in the last 14 days

Timeline

Screening 3 weeks

Treatment Varies

Follow Up anticipated to complete data analysis by december 2023

Awards & highlights

No Placebo-Only Group

Summary

This trial looks at motor memory in people with long COVID vs. healthy adults, by having them complete typing and questionnaire tasks online.

Who is the study for?

This trial is for adults aged 18-90 who have recovered from COVID-19 but may experience long-term effects, known as long COVID. Participants must be able to type with their nondominant hand and have internet access. They cannot join if they've had recent fever or respiratory symptoms, unresolved neurologic symptoms post-COVID, or pre-existing conditions like large strokes or severe psychiatric disorders.

What is being tested?

The study aims to test motor memory in people with long COVID by having them perform typing tasks using their nondominant hand over two days. The tasks are completed online and involve repeatedly typing a number sequence within specific time intervals followed by questionnaires about their experiences.

What are the potential side effects?

Since the intervention involves only keypresses on a keyboard, there are no direct medical side effects associated with this trial. However, participants should not experience discomfort while typing.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I do not have COVID-19 and am not experiencing lingering symptoms.

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I am recovering from COVID-19 and enrolled in a specific NIH post-COVID study.

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I am between 18 and 90 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I haven't had a fever, respiratory symptoms, or COVID-19 in the last 14 days.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ anticipated to complete data analysis by december 2023

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~anticipated to complete data analysis by december 2023

This trial's timeline: 3 weeks for screening, Varies for treatment, and anticipated to complete data analysis by december 2023 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

To investigate differences in procedural memory formation and consolidation during a keyboard typing task between o patients withpersistent symptoms following COVID- 19 infection ( long COVID )and matched controls who deny symptoms of ...