Project YES for Depression and Anxiety

Age: < 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

No Placebo Group

Trial Summary

What is the purpose of this trial?

This study tests a suite of single-session intervention (SSI) targeting risk factors for depression and eating disorders among adolescents and young adults. Youth ages 13-25 who screen positive for depression or anxiety as a part of routine care will be offered one of three digital SSIs. Participants will complete questionnaires before the intervention, immediately after the intervention, and 3-months after completing the intervention so that the study team can investigate if Project YES leads to reductions in depression, anxiety and eating disorder symptoms.

Research Team

Eligibility Criteria

This trial is for young people aged 13-25 who show signs of depression or anxiety during regular check-ups. It's designed to help those at risk for eating disorders and depression.

Inclusion Criteria

Patient at Lurie Division of Adolescent and Young Adult Medicine

I am between 13 and 25 years old.

Provider agreement that this would be an appropriate intervention

Exclusion Criteria

Imminent risk for suicide as indicated by a 'Yes' response to questions #5 on the Ask Suicide Questions (ASQ) Screener

I cannot speak or understand English or Spanish.

Treatment Details

Interventions

• Project YES (Behavioral Intervention)

Trial Overview Project YES involves digital single-session interventions (SSIs) aimed at reducing the risk factors associated with depression, anxiety, and eating disorders. The effectiveness will be measured through questionnaires administered before, immediately after, and three months post-intervention.

Participant Groups

Group I: Project YES Experimental Treatment 1 Intervention

This is a digital, self-guided SSI that has 3 options, Project Personality, Project CARE, and the ABC project. These teach adolescents about CBT skills including growth mindset, neutral self-talk and behavioral activation. Each option contains self-reflection exercises, vignettes from fictional peers, and psychoeducation that support users in understanding each CBT skill. See all materials for this intervention here: https://www.schleiderlab.org/yes.html

Who Is Running the Clinical Trial?

Ann & Robert H Lurie Children's Hospital of Chicago

Lead Sponsor

Trials

275

Recruited

5,182,000+

Dr. Michael D. Kelleher

Ann & Robert H Lurie Children's Hospital of Chicago

Chief Medical Officer since 2012

MD from University of Chicago

Dr. Thomas Shanley

Ann & Robert H Lurie Children's Hospital of Chicago

Chief Executive Officer since 2019

MD from University of Chicago Pritzker School of Medicine

American Psychological Association Division 53 Society for Clinical Child & Adolescent Psychology

Collaborator

Trials

1

Recruited

100+