Pharmacist-Led Therapy for Gout
(Pham-UP Trial)

Recruiting in Palo Alto (17 mi)

+4 other locations

Overseen byTed R. Mikuls

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: VA Office of Research and Development

No Placebo Group

Trial Summary

What is the purpose of this trial?This study will compare two different approaches to manage medications that lower uric acid levels. This study will be conducted at five VA medical centers across the United States and will take 4-5 years to complete. Individual participation will last up to two years.

Eligibility Criteria

This trial is for individuals with gout, a type of arthritis caused by excess uric acid. Participants should be receiving care at one of the five participating VA medical centers and willing to follow treatment for up to two years.

Inclusion Criteria

Patients must satisfy ACR/EULAR gout classification criteria

I have experienced one or more flares in the last 6 months.

I am a US Veteran over 18 with high uric acid levels.

+1 more

Exclusion Criteria

I cannot tolerate or take gout medications like allopurinol or febuxostat.

I saw a rheumatologist in the last 3 months.

Participant Groups

The study is testing a pharmacist-led approach to managing medications that lower uric acid levels in patients with gout. It compares this method against standard practices over a period of 4-5 years across multiple sites.

2Treatment groups

Experimental Treatment

Active Control

Group I: Pharmacist-LedExperimental Treatment1 Intervention

Veterans will participate in regular telehealth visits with study pharmacists. Serum urate lab tests will be ordered during dose escalation phase of gout treatment.

Group II: Usual careActive Control1 Intervention

Veterans will receive standard care from their primary care provider for the management of their gout.