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Beta-blocker

Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction (HFpEF-BB Trial)

N/A
Waitlist Available
Led By Kai Chen, MD,PhD
Research Sponsored by UConn Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and after 4 weeks of beta blocker discontinuation
Awards & highlights
No Placebo-Only Group

Summary

This trial will evaluate how well a heart medication works in 30 patients with heart failure.

Eligible Conditions
  • Heart Failure

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and after 4 weeks of beta blocker discontinuation
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and after 4 weeks of beta blocker discontinuation for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in KCCQ-23 score
Secondary study objectives
6 minute walk test
Changes in biomarker
Changes in cardiac mechanics by echocardiography

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: HFpEF patientsExperimental Treatment1 Intervention
HFpEF patient who are currently taking beta blockers

Find a Location

Who is running the clinical trial?

UConn HealthLead Sponsor
215 Previous Clinical Trials
60,691 Total Patients Enrolled
2 Trials studying Heart Failure
1,050 Patients Enrolled for Heart Failure
Kai Chen, MD,PhDPrincipal InvestigatorUConn Health
~7 spots leftby Jan 2026