← Back to Search

Unknown

ARD-101 for Obesity

Phase 2
Waitlist Available
Research Sponsored by Aardvark Therapeutics, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up run-in visit (baseline)

Summary

This trial is testing ARD-101, a medication taken regularly, in obese individuals with a BMI between 30 and 45. The drug works by interacting with taste receptors to help manage weight.

Eligible Conditions
  • Obesity

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~screening, days 1, 15, and 28
This trial's timeline: 3 weeks for screening, Varies for treatment, and screening, days 1, 15, and 28 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Relative Change in Body Weight (%)
Secondary study objectives
Change in Blood Lipid Concentrations
Change in Hemoglobin A1c
Change in Waist Circumference
+1 more
Other study objectives
Area under the Curve (AUC) of Serum Levels of Glucose, Insulin, and C-peptide during MMTT
Body Fat Percentage
Categorical Weight Loss
+11 more

Side effects data

From 2023 Phase 2 trial • 12 Patients • NCT05215847
17%
Mild Nausea
8%
Mild Emesis
8%
Mild Constipation
8%
Mild Hypoglycemia
8%
Mild Common Cold
8%
Mild Headache
8%
Mild Heart Burn
8%
Mild COVID-19
8%
Mild Dyspepsia
100%
80%
60%
40%
20%
0%
Study treatment Arm
ARD-101

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: ARD-101Experimental Treatment1 Intervention
Dose 200 mg of ARD-101, twice daily for 28 days
Group II: Placebo ComparatorPlacebo Group1 Intervention
Placebo arm matching active arm ARD-101, 200 mg BID
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ARD-101
2021
Completed Phase 2
~40

Find a Location

Who is running the clinical trial?

Aardvark Therapeutics, Inc.Lead Sponsor
3 Previous Clinical Trials
42 Total Patients Enrolled
1 Trials studying Obesity
12 Patients Enrolled for Obesity
University of California, San DiegoOTHER
1,180 Previous Clinical Trials
1,575,036 Total Patients Enrolled
52 Trials studying Obesity
7,462 Patients Enrolled for Obesity
~5 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top