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Cancer Vaccine

Wild Blueberries for High Blood Pressure

N/A
Recruiting
Led By Rafaela G Feresin, PhD
Research Sponsored by Georgia State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Individuals 45-65 years of age
Be older than 18 years old
Must not have
Use of one hypertensive drug for less than three months
Consuming antioxidant, probiotic, and prebiotic supplements
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 4 weeks, 8 weeks

Summary

This trial aims to see if eating wild blueberries can improve heart health, brain function, and the balance of gut bacteria in Black and White adults with high blood pressure.

Who is the study for?
Adults aged 45-65 with slightly high blood pressure (120-139/80-89 mmHg) for at least 6 months, a BMI of 25-30, and the ability to consent can join. Excluded are those on certain medications, with active cancer or major health issues, smokers, heavy drinkers, pregnant women, and those allergic to berries.
What is being tested?
The trial is testing if wild blueberries improve heart health, brain function, and gut bacteria in non-Hispanic Black and White adults with elevated blood pressure compared to a placebo.
What are the potential side effects?
Wild blueberries are generally safe but may cause mild digestive discomfort or allergic reactions in sensitive individuals. The placebo is unlikely to have side effects.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 45 and 65 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have been on blood pressure medication for less than 3 months.
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I take antioxidant, probiotic, and prebiotic supplements.
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I am not using multiple drugs for high blood pressure, insulin, antibiotics, or anti-inflammatory drugs, and I do not have active cancer or major health issues.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 4 weeks, and 8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 4 weeks, and 8 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Ambulatory Blood Pressure
Pulse Wave Velocity
Secondary study objectives
Associative Memory
Attention
Cognitive Inhibition
+8 more
Other study objectives
Body Fat
Circulating Markers of Inflammation and Oxidative Stress
Percent Maximal Microvascular Blood Flow
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Wild BlueberryExperimental Treatment1 Intervention
22 g of freeze-dried wild blueberry freeze-dried powder per day
Group II: PlaceboPlacebo Group1 Intervention
22 g of freeze-dried macronutrient-matched placebo powder per day

Find a Location

Who is running the clinical trial?

Georgia State UniversityLead Sponsor
65 Previous Clinical Trials
30,626 Total Patients Enrolled
Rafaela G Feresin, PhDPrincipal InvestigatorGeorgia State University
1 Previous Clinical Trials
30 Total Patients Enrolled
~53 spots leftby Dec 2025
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