Blueberry Supplements for Depression

Recruiting in Palo Alto (17 mi)

Overseen byCourtney Millar, PhD

Age: 65+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Hebrew SeniorLife

Approved in 2 Jurisdictions

Trial Summary

What is the purpose of this trial?

This trial tests if powdered blueberries can help older adults with depression feel better and become more active by reducing inflammation.

Eligibility Criteria

This trial is for sedentary adults aged 65 or older with mild depressive symptoms. Participants must spend a lot of time sitting and not have cognitive impairments, diabetes, substance abuse issues, severe psychiatric disorders, inflammatory bowel conditions, allergies to the products used in the study, or be taking certain medications like antibiotics or antidepressants.

Inclusion Criteria

I have mild to moderate depression.

I am 65 years old or older.

Self-reporting ≥ 8 hours of sitting per/day (e.g., sedentary behavior)

Exclusion Criteria

Self-reporting a history of inflammatory bowel disease/syndrome, major depression, bipolar, schizophrenia, or other psychotic disorders, or per discretion of the PI

I walk more than 7,500 steps a day, or my doctor agrees I'm active enough.

Cognitive impairment (defined as Montreal Cognitive Assessment, MoCA <22 points)

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Treatment Details

Interventions

Freeze-dried Blueberry Powder (Other)
Placebo Powder (Other)

Trial OverviewThe study tests if daily freeze-dried blueberry powder can help reduce inflammation and improve motivation to be active compared to a placebo powder. It's designed for older adults who don't exercise much and feel down sometimes.

Participant Groups

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Freeze-dried Blueberry PowderExperimental Treatment1 Intervention

Randomized participants will be asked to consume 48 grams of freeze-dried blueberry powder each day for 12 weeks.

Group II: Placebo PowderPlacebo Group1 Intervention

Randomized participants will be asked to consume 48 grams of a nutritionally matched placebo powder devoid of fiber and anthocyanins each day for 12 weeks.

Freeze-dried Blueberry Powder is already approved in United States, European Union for the following indications:

🇺🇸 Approved in United States as Freeze-dried Blueberry Powder for: