~33 spots leftby Apr 2028

Positive Psychology for Irritable Bowel Syndrome

EN
EM
Overseen ByEmmett McGranaghan, BS
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Massachusetts General Hospital
No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to examine the feasibility, acceptability, preliminary efficacy, and candidate gut-brain mechanisms of an optimized positive psychology (PP) intervention for patients with irritable bowel syndrome (IBS), entitled "WISH," compared to an educational control intervention.

Research Team

EN

Elizabeth N Madva, MD

Principal Investigator

Massachusetts General Hospital

Eligibility Criteria

This trial is for individuals with Irritable Bowel Syndrome (IBS). Participants should be interested in exploring non-medical treatments focused on mental well-being. Specific eligibility criteria are not provided, but typically include age range, symptom severity, and willingness to adhere to the study protocol.

Inclusion Criteria

English fluency and access to a phone
I have been diagnosed with IBS according to Rome IV criteria.

Exclusion Criteria

Severe psychiatric illness: Current manic episode, psychosis, or active substance use disorder diagnosed via the Mini International Neuropsychiatric Interview (MINI)
Cognitive impairment assessed using a six-item cognitive screen developed for research
I plan to begin a new mental health treatment during the study.

Treatment Details

Interventions

  • Educational Intervention (Behavioral Intervention)
  • Positive Psychology (PP) Intervention (Behavioral Intervention)
Trial OverviewThe WISH 2.0 study is testing an optimized positive psychology intervention against an educational control intervention to see which one better improves the quality of life for IBS patients. It looks at how acceptable and effective these approaches are and their impact on gut-brain interactions.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Positive Psychology (PP) InterventionExperimental Treatment1 Intervention
Participants will complete an adapted, optimized, phone-based, 9-week positive psychology (PP) intervention.
Group II: Educational InterventionActive Control1 Intervention
Participants will complete a 9-week, phone-based educational intervention that matches the PP intervention in terms of both time and attention.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Massachusetts General Hospital

Lead Sponsor

Trials
3,066
Recruited
13,430,000+