Hyaluronic + Corticosteroid Injections and Physical Therapy for Hip Issues

(NON-OP HIP Trial)

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: ArthroBiologix Inc.

No Placebo Group

Trial Summary

What is the purpose of this trial?

Hip pathologies that cause pain and functional limitations are common in the general population. These can include femoroacetabular impingement (FAI), labral tears and mild osteoarthritis (OA) among others. While more severe and symptomatic cases may require surgical intervention, the treatment of mild-to-moderate cases is often treated without surgery to relieve pain, improve function, and delay surgical intervention. Non-operative treatments of hip pathologies consist of a multitude of options. A common non-operative intervention includes intra-articular injections, including corticosteroids and hyaluronic acid. Evidence has demonstrated that corticosteroids have fast acting effects which tend to diminish within a few months, while hyaluronic acid has a delayed time of onset and demonstrates clinical benefit for a longer period of time. Studies have evaluated combinations of corticosteroid and hyaluronic acid, hoping to take advantage of the fast-acting relief of corticosteroid and the longer lasting benefits of corticosteroid. Physiotherapy is also a frequent non-operative intervention used to relieve pain and increase function in patients with hip pathologies. While many studies have looked at intra-articular injections and physiotherapy as independent non-operative possibilities for hip conditions, the combined effect of these two have not received much evaluation. The purpose of this study is to evaluate the effect of physiotherapy in conjunction with a combined corticosteroid and hyaluronic acid intraarticular injection on patient outcomes when compared to a corticosteroid and hyaluronic acid intraarticular injection alone.

Research Team

Eligibility Criteria

This trial is for individuals with mild-to-moderate hip pain and functional limitations due to conditions like femoroacetabular impingement, labral tears, or osteoarthritis. It's not suitable for those needing surgery or who have severe symptoms.

Inclusion Criteria

Able to subsidize private physiotherapy services

Able to provide informed consent

I am between 40 and 60 years old.

Exclusion Criteria

Injuries sustained in the workplace and have a worker's compensation claim

I have had surgery on my pelvis, hip, or lower limb.

Injuries sustained in a motor vehicle collision

Treatment Details

Interventions

• Intra-articular Corticosteroid (Corticosteroid)
• Physiotherapy (Other)

Trial Overview The study tests if combining a corticosteroid and hyaluronic acid injection with physiotherapy improves outcomes in hip pathology patients compared to the injection alone.

Participant Groups

Group I: Hyaluronic and corticosteroid injection with physical therapy Experimental Treatment 2 Interventions

Patients will receive an ultrasound-guided injection consisting of 3 ml hyaluronic acid (Durolane™) mixed with 40 mg triamcinolone (Kenalog™) into their hip joint. Patients will also receive an 8-week physiotherapy protocol, consisting of 8 visits. The protocol will consist of 1 visit per week.

Group II: Hyaluronic and corticosteroid injection Active Control 1 Intervention

Patients will receive an ultrasound-guided injection consisting of 3 ml hyaluronic acid (Durolane™) mixed with 40 mg triamcinolone (Kenalog™) into their hip joint.

Who Is Running the Clinical Trial?

ArthroBiologix Inc.

Lead Sponsor

Trials

2

Recruited

260+