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Brain Stimulation for Memory Enhancement During Sleep Cycles
Los Angeles, CA
N/A
Recruiting
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks
Awards & highlights
No Placebo-Only Group
Summary
This trial will study how people's brains process and store memories while they sleep, by recording brain activity at different levels of resolution. They will also study how different types of stimulations during sleep can affect memory processes.
See full description
Who is the study for?
This trial is for epilepsy patients aged 18-65 undergoing depth electrode placement. They must be willing to consent and participate, as determined by the epilepsy surgery team after neuropsychological and psychiatric evaluation. Those with additional neurological or psychiatric conditions posing risks are excluded.
What is being tested?
The study aims to understand memory processes during sleep by recording brain activity in humans through various methods. It will also explore how auditory and electrical stimulations applied during sleep can affect memory consolidation.
What are the potential side effects?
Since this trial involves non-pharmacological interventions like auditory and electrical stimulation, side effects may include discomfort at the electrode sites, potential sleep disturbances, or temporary changes in mood or cognition.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Recognition Accuracy
Recognition Discriminability (D-prime)
Secondary study objectives
Neuronal replay index
Power sleep oscillations
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Find a Location
Closest Location:University of California Los Angeles· Los Angeles, CA· 1181 miles
Who is running the clinical trial?
National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,398 Previous Clinical Trials
655,952 Total Patients Enrolled
University of California, Los AngelesLead Sponsor
1,584 Previous Clinical Trials
10,421,512 Total Patients Enrolled
University of IowaOTHER
483 Previous Clinical Trials
933,355 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am an epilepsy patient aged 18-65 and will have a depth electrode placement.I am either younger than 18 or older than 65.I have no major mental or neurological issues, except for epilepsy.
Research Study Groups:
This trial has the following groups:Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.