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Short-Chain Fatty Acid

Tributyrin for Health and Performance (CoreBiome Trial)

N/A
Recruiting
Research Sponsored by Florida State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age: 30-50 years
Be between 18 and 65 years old
Must not have
Chronic, uncontrolled metabolic, cardiovascular, gastrointestinal, or hepatic disease
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 minutes before and 5 minutes prior to completion of exercise bout (i.e., mid-exercise)

Summary

This trial aims to investigate whether taking tributyrin supplements can improve the health, performance, and metabolite concentrations in inactive men and women. The study will examine how tributyrin may enhance

Who is the study for?
This trial is for sedentary men and women who may have metabolic disorders, leaky gut syndrome, inflammation issues, sleep disturbances or performance anxiety. Participants will be required to take supplements and undergo various health assessments over a 4-week period.
What is being tested?
The study tests whether tributyrin (CoreBiome) can improve metabolite concentrations, overall health biomarkers, and performance compared to a placebo. It involves fecal metabolite measures, cardiovascular evaluation, sleep assessment, exercise testing and blood samples.
What are the potential side effects?
Potential side effects are not detailed in the provided information. However, as with any supplement intake there could be risks of digestive discomfort or allergic reactions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 30 and 50 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I do not have any long-term unmanaged heart, liver, stomach, or metabolic conditions.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during exercise bout
This trial's timeline: 3 weeks for screening, Varies for treatment, and during exercise bout for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Metabolite Concentration
Secondary study objectives
Average sprint power (mid-exercise)
Gut permeability
Immune cell composition
+7 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: CoreBiomeActive Control1 Intervention
Participants will be given tributyrin (as CoreBiome)
Group II: PlaceboPlacebo Group1 Intervention
Participants will be given a taste-, color-, and odor-matched placebo

Find a Location

Who is running the clinical trial?

Compound Solutions Inc.UNKNOWN
4 Previous Clinical Trials
225 Total Patients Enrolled
Florida State UniversityLead Sponsor
219 Previous Clinical Trials
36,411 Total Patients Enrolled
1 Trials studying Inflammation
62 Patients Enrolled for Inflammation
~13 spots leftby Jul 2025
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