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Implicit Priming for Obesity

N/A

Recruiting

Led By Jason Tregellas, PhD

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age between 18-65 years old

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 12 weeks

Summary

This trial will test how different ways of thinking about food can affect eating habits and weight.

Who is the study for?

This trial is for adults aged 18-65 with obesity, defined as having a BMI of 27 or greater. It's not suitable for pregnant individuals or those who cannot undergo MRI scans due to metal or electronic devices in their body.

What is being tested?

The study tests how 'Active Implicit Priming' and 'Control Implicit Priming' interventions influence brain reactions to food, eating habits, and weight when compared to a 'Food Exposure Task'.

What are the potential side effects?

Since this trial involves behavioral interventions rather than medications, side effects may include discomfort from discussing eating habits or undergoing MRIs but are generally minimal.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 65 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in Food Image Ratings

Change in Food Intake

Percent Change in Blood Oxygen Level Dependent (BOLD) Response to Visual Food Cues as Measured by Functional Magnetic Resonance Imaging

Secondary study objectives

Change in Fat Mass

Percent Change in Body Weight

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Active Implicit PrimingExperimental Treatment1 Intervention

Participants will complete active implicit priming, in which food images are implicitly primed (i.e., below conscious awareness) with images of positive or negative affect. This will be completed on a weekly basis for 12 weeks, for approximately 10 minutes each time.

Group II: Food Exposure TaskActive Control1 Intervention

Participants will complete a Food Exposure Task, in which they will be asked to smell, feel, lick, and imagine eating food items, but without actually eating them. This will be completed on a weekly basis for 12 weeks, for approximately 10-30 minutes each time.

Group III: Control Implicit PrimingPlacebo Group1 Intervention

Participants will complete control implicit priming, which matches the active intervention, but with neutral stimuli as primes. This will be completed on a weekly basis for 12 weeks, for approximately 10 minutes each time.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Active Implicit Priming

2013

N/A

~100

0 / 1Eligibility criteria met