Social Network Intervention for Opioid Overdose

Overseen by Carl A. Latkin, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Johns Hopkins Bloomberg School of Public Health

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to pilot and implement a peer mentor intervention focused on overdose prevention and care. The intervention consists of 3 sessions. During the first and second session, each participant will meet individually with a trained staff member. In the 3rd session, the participant will invite a social network member to attend the session, and these 2 participants will meet with a trained staff member.

Research Team

Carl A. Latkin, PhD

Principal Investigator

Johns Hopkins Bloomberg School of Public Health

Eligibility Criteria

This trial is for adults over 18 living in the Baltimore area who use opiates like heroin, fentanyl, or prescription drugs to get high at least twice in the past two weeks. They must see a friend they can invite to the study twice a week and not be part of another Lighthouse study.

Inclusion Criteria

You have met the person being studied two or more times in the past week.

You live in the Baltimore area.

You must be at least 18 years old.

Treatment Details

Interventions

• Narcan Nasal Product (Opioid Antagonist)
• Peer Education (Behavioral Intervention)

Trial Overview The study tests a peer mentor program aimed at preventing opioid overdoses. Participants will have three sessions with trained staff; one includes bringing someone from their social network to learn about overdose prevention together.

Participant Groups

Group I: Peer Education Experimental Treatment 2 Interventions

* During Session 1, participants will be trained in Peer Education and how to use Nasal Narcan. They will be given two Nasal Narcan kit that includes 2 doses. One kit if for their use and one kit is to give someone in their social network after they have trained them in how to use it. * A week after Session 1, participants will be scheduled for Session 2. * During session 1 and 2 participants, Index participants will be taught information and skills pertaining to overdose prevention and response and how to train network members in overdose prevention and response. * At the 2nd session, index participants will be given 1 coupon to give to 1 member from their social network to attend Session 3. * Session 3 will be a dyad session where Index participants will use their peer mentors' skills to train their network member in overdose prevention and response. * Index participants will also be invited to up to 3 Booster Session (monthly) after they complete Sessions 1-3.

Group II: Standard of care Active Control 1 Intervention

* Participants randomized to this condition will participate in one 1-hour session. This session will be an individual session where the participant will meet with a trained staff member in a private room at the Lighthouse. * This session will be standard overdose prevention and response information. Participants will also be trained in Narcan administration. Participants will be given 1 nasal Narcan kit. * At the end of this session, participants will be asked to refer a network member to the study for survey visits

Who Is Running the Clinical Trial?

Johns Hopkins Bloomberg School of Public Health

Lead Sponsor

Trials

441

Recruited

2,157,000+

Dr. Joshua M. Sharfstein

Johns Hopkins Bloomberg School of Public Health

Chief Medical Officer since 2015

MD from Johns Hopkins University

Dr. Ellen J. MacKenzie

Johns Hopkins Bloomberg School of Public Health

Chief Executive Officer since 2017

MD from Johns Hopkins University

Centers for Disease Control and Prevention

Collaborator

Trials

902

Recruited

25,020,000+

Dr. Debra Houry

Centers for Disease Control and Prevention

Chief Medical Officer

MD, MPH

Dr. Susan Monarez

Centers for Disease Control and Prevention

Chief Executive Officer

PhD