Strength Training for Osteoporosis

(STOP-EM Trial)

Overseen by Leigh Gabel, PhD

Age: 18 - 65

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Calgary

No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this clinical pilot trial is to learn about the feasibility of a high-intensity resistance training intervention in peri- and early menopausal females. The main question it aims to answer are: -Is a 9-month resistance training intervention feasible (e.g., recruitment rates, protocol adherence, attrition) Secondary aims include examining changes in bone health, muscle strength, and menopausal symptoms. Participants will participate in a 9-month progressive, supervised, resistance training intervention. Researchers will compare secondary outcomes between the exercise group and a wait-list control group.

Research Team

Leigh Gabel, PhD

Principal Investigator

University of Calgary

Eligibility Criteria

This trial is for women aged 45-60 who are in peri- or early menopause, not currently doing resistance training, and have no recent severe fractures or conditions worsened by exercise. They shouldn't be pregnant nor planning pregnancy soon, without metabolic bone diseases, active steroid use, or low vitamin D/calcium levels.

Inclusion Criteria

I am in the early or peri-menopausal stage, within 5 years of my last period.

I am between 45 and 60 years old.

Exclusion Criteria

I have had a bone fracture due to osteoporosis in the last 5 years.

I am not pregnant nor planning to become pregnant in the next year.

Your blood test shows low levels of vitamin D or calcium.

Treatment Details

Interventions

• Resistance Training (Behavioural Intervention)

Trial Overview The study tests if a high-intensity resistance training program over 9 months is practical for participants to follow. It will also look at the effects on bone health, muscle strength, and menopausal symptoms compared to a group that waits to start the program.

Participant Groups

Group I: Exercise Experimental Treatment 1 Intervention

In-person, supervised resistance training program

Group II: Control Active Control 1 Intervention

Waitlist control group. Will be offered the exercise program following a 9-month wait.

Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials

827

Recruited

902,000+