Nerve Stimulation for Peripheral Neuropathy
Trial Summary
What is the purpose of this trial?
To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Peripheral Nerve Stimulation for Peripheral Neuropathy?
Peripheral Nerve Stimulation (PNS) has been shown to provide significant pain relief in cases where other treatments have failed, such as intractable neuropathic pain after surgery. It is effective for various chronic pain conditions, including neuropathic pain, and recent advancements in PNS technology have improved its safety and effectiveness.12345
How is Peripheral Nerve Stimulation treatment different from other treatments for peripheral neuropathy?
Peripheral Nerve Stimulation (PNS) is unique because it uses electrical currents to target specific nerves, reducing pain by altering nerve signal transmission. Unlike other treatments, PNS can be noninvasive, using an external probe on the skin, and is often used when other treatments have failed.13456
Research Team
Saba Javed, MD
Principal Investigator
M.D. Anderson Cancer Center
Eligibility Criteria
This trial is for adults aged 18-85 with long-term pain from nerve damage caused by certain chemotherapy drugs or radiation, who have finished chemo within the last year. They must be patients at MD Anderson's Pain Management Center and report a pain level of 4 or higher on a scale to 10. People with cognitive issues, recent substance abuse, skin infections, allergies to specific medical materials, pregnancy, or conditions conflicting with the PNS device can't join.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive peripheral nerve stimulation (PNS) with leads inserted via a needle, providing a mild electrical current to the affected nerves 24 hours a day for up to 60 days
Follow-up
Participants are monitored for safety and effectiveness after treatment, including assessments of pain intensity, sensory testing, gait testing, and skin punch biopsy
Long-term follow-up
Monitoring for safety and adverse events, graded according to NCI CTCAE v5.0
Treatment Details
Interventions
- Peripheral Nerve Stimulation (Procedure)
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
Dr. Peter WT Pisters
M.D. Anderson Cancer Center
Chief Executive Officer since 2017
MD from University of Western Ontario
Dr. Jeffrey E. Lee
M.D. Anderson Cancer Center
Chief Medical Officer
MD from Stanford University School of Medicine