Nerve Stimulation for Peripheral Neuropathy

Palo Alto (17 mi)

Overseen bySaba Javed, MD

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Recruiting

Sponsor: M.D. Anderson Cancer Center

No Placebo Group

Approved in 2 jurisdictions

Trial Summary

What is the purpose of this trial?To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.

Eligibility Criteria

This trial is for adults aged 18-85 with long-term pain from nerve damage caused by certain chemotherapy drugs or radiation, who have finished chemo within the last year. They must be patients at MD Anderson's Pain Management Center and report a pain level of 4 or higher on a scale to 10. People with cognitive issues, recent substance abuse, skin infections, allergies to specific medical materials, pregnancy, or conditions conflicting with the PNS device can't join.

Inclusion Criteria

I have long-term nerve pain in my legs due to cancer treatment.

My pain level is 4 or higher on a scale of 0 to 10.

I am between 18 and 85 years old.

Exclusion Criteria

I have an open skin wound or am on antibiotics for an infection.

Treatment Details

The study is testing whether Peripheral Nerve Stimulation (PNS), which involves sending electrical signals to nerves through small devices placed under the skin, can reduce pain in people suffering from chronic chemotherapy-induced peripheral neuropathy (CIPN) in their lower extremities.

1Treatment groups

Experimental Treatment

Group I: Peripheral Nerve StimulationExperimental Treatment1 Intervention

Participants will be asked to have PNS leads inserted via a needle, which will provide a mild, stimulating electrical current to the effected nerves 24 hours a day for up to 60 days. Participants will have study visits during and after this time.

Peripheral Nerve Stimulation is already approved in United States, European Union for the following indications:

🇺🇸 Approved in United States as PNS for: