Trial Summary
What is the purpose of this trial?This study seeks to understand emotion regulation in those with young adults with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity. The goal of this project is to understand how receiving feedback about one's own brain activity relates to emotion regulation ability. This work will help the study team understand the brain areas involved in emotion regulation and could lay the groundwork to test if psychotherapy outcomes can be enhanced using neurofeedback.
The study hypotheses include:
* Participants receiving veritable-Neurofeedback (NF) will show a greater activation increases in the ventrolateral prefrontal cortex (vlPFC) compared to sham-NF
* Participants receiving veritable-NF will show greater cognitive reappraisal (CR) ability compared to those receiving sham-NF
* vlPFC activation will positively correlate with CR ability
Eligibility Criteria
This trial is for young adults with anxiety disorders such as social anxiety, generalized anxiety, and panic disorder. Participants should be interested in using neurofeedback to potentially improve emotion regulation.Inclusion Criteria
I have been diagnosed with an anxiety disorder.
Exclusion Criteria
I have been diagnosed with OCD or PTSD.
I have a serious brain condition or illness affecting my brain function.
I have had a severe head injury with unconsciousness, hospital stay, or lasting effects.
Treatment Details
The study tests if real-time feedback on brain activity (veritable-Neurofeedback) can enhance cognitive reappraisal ability better than sham Neurofeedback (placebo). It uses fMRI to monitor changes in the ventrolateral prefrontal cortex.
2Treatment groups
Experimental Treatment
Active Control
Group I: Veritable-NFExperimental Treatment1 Intervention
Group II: Sham-NFActive Control1 Intervention
Find a clinic near you
Research locations nearbySelect from list below to view details:
University of MichiganAnn Arbor, MI
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Who is running the clinical trial?
University of MichiganLead Sponsor
National Institute of Mental Health (NIMH)Collaborator