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Avocado Snacks for Prediabetes (AVOC4 Trial)

N/A
Waitlist Available
Led By Britt Burton-Freeman, ph.D
Research Sponsored by Clinical Nutrition Research Center, Illinois Institute of Technology
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up time 0-180 minutes

Summary

This trial found that three different evening snacks had different effects on morning fasting glucose and insulin concentrations in individuals with prediabetes.

Who is the study for?
This trial is for men and women aged 25-70 with prediabetes, defined as fasting blood glucose between 100-125 mg/dL. Participants should be nonsmokers in good health without cardiovascular or metabolic diseases, not on interfering medications, and able to follow the study's diet and testing protocols.
What is being tested?
The study compares three evening snacks: low-fat yogurt; avocado; and a combination of low-fat yogurt with added fiber and fat. It aims to observe their effects on morning fasting glucose levels as well as post-meal insulin concentrations in prediabetic individuals.
What are the potential side effects?
Potential side effects are not explicitly listed but may include digestive discomfort due to dietary changes. As this is a nutritional intervention trial focusing on common foods, significant side effects are unlikely.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~time 0-180 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and time 0-180 minutes for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in plasma Interleukin (IL)-6 concentration
Changes in plasma glucose concentration
Changes in plasma insulin concentration
+2 more

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: control snackExperimental Treatment1 Intervention
Low-fiber, low-fat
Group II: Avocado snackExperimental Treatment1 Intervention
1 avocado
Group III: control snack + fiber supplement + vegetable oilPlacebo Group1 Intervention
high fat, high fiber control

Find a Location

Who is running the clinical trial?

Hass Avocado BoardOTHER
12 Previous Clinical Trials
711 Total Patients Enrolled
Clinical Nutrition Research Center, Illinois Institute of TechnologyLead Sponsor
54 Previous Clinical Trials
2,950 Total Patients Enrolled
Britt Burton-Freeman, ph.DPrincipal InvestigatorIllinois Institute of Technology
~14 spots leftby Dec 2025
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