Inspiratory Muscle Training for Menopausal Hot Flashes

Overseen By Pamela Engrav

Age: 18 - 65

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: Mayo Clinic

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this research is to understand how training the muscles used for breathing (inhalation) affects menopausal hot flashes, sympathetic nerve activity and sleep.

Research Team

Sarah Baker, PhD

Principal Investigator

Mayo Clinic

Eligibility Criteria

This trial is for midlife women experiencing menopausal hot flashes, with or without hypertension. Participants should be interested in trying a breathing exercise program using the POWERbreathe K3 device to potentially improve their symptoms.

Inclusion Criteria

Participants will be recruited from Rochester, MN and surrounding areas

Non-smokers

I am a woman aged 45-60 experiencing hot flashes.

Exclusion Criteria

I have been on stable hormone therapy or heart medication for over 3 months.

I use sleep aids like prescription drugs or supplements.

I don't have a history of lung collapse, unhealed perforated eardrum, or similar conditions.

Treatment Details

Interventions

• High-Resistance Inspiratory Muscle Strength Training (Behavioral Intervention)
• Low-Resistance Inspiratory Muscle Strength Training (Behavioral Intervention)

Trial Overview The study tests if strengthening the muscles used for breathing can help reduce hot flashes, affect nerve activity related to stress response, and improve sleep quality in menopausal women. It compares high-resistance against low-resistance training.

Participant Groups

Group I: High-Resistance Inspiratory Muscle Strength Training Group Experimental Treatment 2 Interventions

Subjects will partake in 5 sets of 6 inspiratory maneuvers (total: 30 maneuvers/session) 6 days a week for 6 weeks using the POWERbreathe K3 device to monitor adherence.

Group II: Low-Resistance Inspiratory Muscle Strength Training Group Active Control 2 Interventions

Subjects will partake in 5 sets of 6 inspiratory maneuvers (total: 30 maneuvers/session) 6 days a week for 6 weeks using the POWERbreathe K3 device to monitor adherence.

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+